Center for Translational Environmental Health Research

描述(由申请人提供) 研究人员提出了一个新的“翻译环境健康研究中心”(CTEHR)，以促进综合翻译研究，并催化人类环境健康的跨学科研究。CTEHR的使命是通过整合基础、生物医学和工程研究，从实验室到临床，再到社区和回来，来提高我们对环境对人类健康影响的理解。为实现其使命，反恐执行委员会将以四个广泛目标启动： 目标1：通过成员参与专题重点领域和利用综合健康科学设施核心，建设翻译环境健康科学方面的能力。五个相互关联的专题重点领域的研究重点是环境应激源、个人反应的修饰物和环境影响的人类健康结果。IHSFC将提供独特的资源并利用“翻译导航员”来促进利用和促进CTEHR成员的翻译环境健康研究。 目标2：通过职业发展计划整合跨翻译边界的研究人员和研究活动，并在翻译环境健康领域培养有前途的新研究人员。CTEHR职业发展计划将指导初级调查人员，并通过一个新的中心间“指导伙伴”计划促进职业范围内的职业发展。 目标3：通过设施核心和试点项目方案，加强环境健康科学研究方案的能力。CTEHR设备核心将建立一条“发现管道”，以提供支持假设生成和假设检验研究的资源，这些研究将转化为实践中心成员的研究。试点项目计划支持具有推动环境健康科学研究潜力的早期项目。目标4：在中心成员、周围社区和利益攸关方之间建立一座桥梁，通过社区外联和参与核心(COEC)进一步开展科学合作并传播研究成果。通过促进中心科学家、设施核心和项目人员的参与，COEC将提供资源和专业知识，使个人、社区和政策制定者能够就环境暴露做出明智的决定，并降低环境疾病风险。 德克萨斯医疗中心是世界上最大的医疗中心，拥有大量的研究人员，进行与人类环境健康相关的世界级研究。然而，在这种情况下，不存在任何实体来整合这些有才华的调查人员并利用 这一资源丰富的环境具有促进环境健康科学研究和翻译的能力。CTEHR将通过在TMC及其附属机构中充当环境健康研究的联络人来满足这一需求。

DESCRIPTION (provided by applicant) The investigators propose a new "Center for Translational Environmental Health Research" (CTEHR) to promote integrated translational research, and catalyze interdisciplinary research in human environmental health. The CTEHR Mission is to improve our understanding of environmental influences on human health by integrating basic, biomedical and engineering research across translational boundaries from the laboratory to the clinic and to the community and back. To achieve its mission, the CTEHR will be initiated with four broad goals: Goal 1: Build capacity in translational environmental health sciences through member participation in Thematic Focus Areas and utilization of an Integrated Health Sciences Facility Core (IHSFC). Research in the five interrelated Thematic Focus Areas focuses on environmental stressors, modifiers of individual response and human health outcomes impacted by the environment. The IHSFC will provide unique resources and utilize "Translational Navigators" to facilitate utilization and promote translational environmental health research by CTEHR members. Goal 2: Integrate researchers and research activities across translational boundaries and develop promising new investigators in translational environmental health with a Career Development Program. The CTEHR Career Development Program will mentor junior investigators, and promote professional development all along the career spectrum with a new inter-Center "Mentored Partnership" Program. Goal 3: Enhance the capabilities of research programs in environmental health sciences with Facility Cores and a Pilot Project Program. CTEHR Facility Cores will build a "Discovery Pipeline" to provide resources supporting Hypothesis Generation and Hypothesis Testing studies that Translate into practice Center member research. The Pilot Project Program supports early-stage projects with potential to advance environmental health science research. Goal 4: Create a bridge between Center members, surrounding communities, and stakeholders to further scientific collaborations and dissemination of research results through the Community Outreach and Engagement Core (COEC). By fostering the involvement of Center scientists, Facility Core and Program personnel, the COEC will provide resources and expertise that enable individuals, communities and policy makers to make informed decisions about environmental exposures, and to mitigate environmental disease risks. The Texas Medical Center is the largest medical center in the world, with a wealth of investigators conducting world-class research relevant to human environmental health. However, no entity exists in this setting to integrate these talented investigators and harness the capabilities of this resource-rich environment to promote research and translation of the environmental health sciences. CTEHR will fill this need by serving as the focal point for environmental health research across the TMC and affiliated institutions.