Research Core: Methodology and Statistics

方法和统计核心(MSC)是该中心支持 跨三个研究组成部分的知识集成和接口，管理核心和 飞行员和培训核心。在我们目前P30工作的基础上，我们将整合多学科 多方法分析方法，横跨我们第一类和第二类主题集成计划 翻译研究。MSC将联合多名方法学家，他们的专业知识范围从量化 多变量建模、定性方法和神经成像分析继续推进多方法 分析方法并通过向中心提供支持和培训来促进整个中心的协同效应 科学家、青年职业科学家、少数民族科学家和高级研究生。具体地说， MSC提出了五个具体目标。首先，核心将提供对尖端技术的集中访问 中心研究组成部分和中心科学家的多学科多方法分析方法。 第二，核心将加强预防药物滥用的多学科、多方法分析方法 将创新的定性和神经成像方法整合到定量多变量中的研究 为研究组成部分和试点研究建立模型。第三，促进所有中心的协同 活动，核心将建立一个集中和连贯的数据管理系统，以提供质量 控制来自所有中心研究组件和试点研究的数据。第四，核心将提供 多学科多方法培训和为早期职业科学家、少数民族科学家和 高级研究生，在这些方法中培养未来的领导者。最后，核心将接触到 通过传播从中心学到的知识建立更大的药物滥用预防研究社区 通过讲习班和数据共享开展活动。总体而言，MSC的目标将使我们能够 多学科、多方法解决我们的药物滥用预防研究的目标，并 向中心内外的科学家提供这些改进的统计方法。

The Methodology and Statistics Core (MSC) serves as a key resource for the Center to support the integration and interface of knowledge across three Research Components, the Administrative Core, and the Pilot and Training Core. Building upon our work in the current P30, we will integrate multidisciplinary multimethods analytic approaches that cross-cut our thematically-integrated program of Type I and Type II translational research. The MSC will unite multiple methodologists whose expertise range from quantitative multivariate modeling, qualitative methods, and neuroimaging analyses to continue to advance multi-method analytic approaches and promote synergy across the Center by providing support and training to Center Scientists, Eariy Career Scientists, Minority Scientists, and advanced graduate students. Specifically, the MSC proposes five Specific Aims. First, the Core will provide centralized access to cutting-edge multidisciplinary multimethod analytic approaches for Center Research Components and Center Scientists. Second, the Core will enhance multidisciplinary multimethod analytic approaches in drug abuse prevention research by integrating innovative qualitative and neuroimaging methods into quantitative multivariate modeling forthe Research Components and Pilot Studies. Third, to facilitate synergy across all Center activities, the Core will establish a centralized and coherent data management system to provide quality control for data from all Center Research Components and Pilot Studies. Fourth, the Core will provide multidisciplinary multimethod training and services to Early Career Scientists, Minority Scientists and advanced graduate students to nurture future leaders in these approaches. Finally, the Core will reach out to larger drug abuse prevention research communities by disseminating knowledge learned from Center activities via workshops and data sharing. Overall, the Aims of the MSC will allow us to advance multidisciplinary multimethod approaches to address the goals of our drug abuse prevention research and to make these improved statistical methods available to scientists within and outside of the Center.