The UC DPP Study: Evaluating a Diabetes Prevention Initiative Across the University of California System

项目摘要/摘要 为了解决加州大学(UC)所有校园的肥胖和2型糖尿病预防问题，一项新的 加州大学糖尿病预防倡议(简称UC DPP倡议)于2018年启动。在一个 研究人员与大学之间的创新科学伙伴关系，加州大学校长办公室将 为加州大学受益人提供访问电子健康记录(EHR)和保险索赔的权限，以及 五个UC园区的校园级数据以进行严格的评估。我们将使用一个久负盛名的 REACH、有效性、采用、实施和维护(RE-AIM)评估框架，以确保 综合评价。为了评估UC DPP倡议的有效性，我们将审查Mean 超重/肥胖12个月内和24个月内体重变化百分比(主要结果) UC受益者有患2型糖尿病的风险。为了评估REACH，我们将报告符合条件的UC的比例 参与DPP的受益人(出席&>9和&>16届会议)及其在UC的代表性 总体上是受益者。为了审查采用、实施和维护，我们将进行实地考察和 定性访谈，重点是评估执行程度，确定障碍和促进者 与实施相关，并产生意想不到的后果。总而言之，这是一个独特的机会 使用统一通信系统中的不同数据源进行强制性评估。这项研究的发现 将为未来加州大学范围内针对肥胖和2型糖尿病预防的计划提供信息，以及传播 向其他大型大学系统和雇主提供有效的战略。

PROJECT SUMMARY/ABSTRACT To address obesity and type 2 diabetes prevention across all University of California (UC) campuses, a new UC-wide Diabetes Prevention Initiative (referred to as the UC DPP Initiative) was launched in 2018. In an innovative scientific partnership between researchers and the university, the UC Office of the President will provide access to electronic health record (EHR) and insurance claims for UC beneficiaries, as well as campus-level data across five UC campuses to conduct a rigorous evaluation. We will use a well-established reach, effectiveness, adoption, implementation, and maintenance (RE-AIM) evaluation framework to ensure a comprehensive evaluation. To assess the effectiveness of the UC DPP Initiative, we will examine mean percent weight change at 12-months (primary outcome) and 24-months within and between overweight/obese UC beneficiaries at risk for type 2 diabetes. To assess reach, we will report the proportion of eligible UC beneficiaries who engage in DPP (attend >9 and >16 sessions) and their representativeness of UC beneficiaries overall. To examine adoption, implementation and maintenance, we will conduct site visits and qualitative interviews, focused on assessing the degree of implementation, identifying barriers and facilitators associated with implementation, and unanticipated consequences. In summary, this is a unique opportunity to conduct an imperative evaluation using diverse data sources across the UC system. Findings from this study will inform future UC-wide programs targeting obesity and type 2 diabetes prevention, as well as dissemination of effective strategies to other large university systems and employers.