Data Lakes Meet the Great Lakes: Deep Dives into Diversity in Genomics

项目摘要 北海岸精准医学会议是一个全国性的年度中型会议系列， 克利夫兰，俄亥俄州。该系列会议旨在作为继续教育和交流的场所， 与快速发展和高度跨学科的景观相关的科学思想，即精准医学 research.每次会议的主题都与国家对话和研究议程相吻合， 专注于精准医疗的国家研究计划。2020年和2021年的会议将是专题讨论会 重点关注与转化遗传学和基因组研究相关的广泛主题，包括结构和 基因组生物学;疾病生物学;生物信息学;计算生物学;基因组学应用 改善临床护理;以及伦理、法律的和社会问题。所有选定的研讨会主题将包括一个 在研究中强调不同的人群，这可以从确定和参与者保留 混合种群分析的方法发展战略。会议将以 邀请各国专家在轻松和鼓舞人心的环境中发言的传统形式 在克利夫兰植物园具体的会议主题正在考虑从以前的专题讨论会 精准医学研究的参与者和趋势。奇数年会议包括一个研讨会或 小组活动组成部分，以前涵盖了结果和暴露变量提取， 电子健康记录和研讨会前后对与会者知识的实时调查。未来 正在考虑的研讨会主题包括多组学的整合，不同人群的药物反应， 药物基因组学临床实施，癌症精准医学，数据共享和知情同意， 以及使用应用程序进行招募、诊断、随访和治疗。我们的第二个主要目标 会议系列是促进生物医学劳动力的多样性。众所周知， 从培训到生物医学研究领域的全职教授，女性的工作是有漏洞的， 少数民族的代表实际上是不存在的。从国家和地方的资源中，我们审查妇女， 代表性不足的少数民族为每一个受邀发言的机会，从而提供宝贵的职业货币 网络机会。我们还将鼓励妇女和代表性不足的少数民族，特别是在 学员级别，出席并参加这一系列会议，以激发对追求遗传学的兴趣， 基因组学研究作为职业总的来说，北海岸精准医学系列会议是一个有价值的 除了国家会议景观，并以其独特的位置，低成本的参与者，和旅行 奖项，将作为一个重要的教育机会，因为精准医学研究加速， 认真的

PROJECT SUMMARY The North Coast Conference on Precision Medicine is a national annual mid-sized conference series held in Cleveland, Ohio. The conference series aims to serve as a venue for the continuing education and exchange of scientific ideas related to the rapidly evolving and highly interdisciplinary landscape that is precision medicine research. The topics for each conference coincide with the national conversation and research agenda set by national research programs focused on precision medicine. The 2020 and 2021 conferences will be symposia focused on broad themes relevant to translational genetic and genomic research, including the structure and biology of genomes; the biology of disease; bioinformatics; computational biology; application of genomics to improve clinical care; and ethical, legal and social issues (ELISI). All selected symposium topics will include an emphasis on diverse populations in research, which can range from ascertainment and participant retention strategies to methods development for analysis of admixed populations. The conference will be organized as a traditional format with invited speakers from among national experts set in a relaxing and inspiring environment at the Cleveland Botanical Garden. Specific conference topics are being considered from previous symposia attendees and trends in precision medicine research. Odd-numbered year conferences include a workshop or group activity component which has previously covered outcome and exposure variable extraction from electronic health records and real-time survey of attendee knowledge pre- and post-symposium. Future workshop topics being considered include integration of multiple ‘omics, drug response in different populations, pharmacogenomics clinical implementation, precision medicine in cancer, data sharing and informed consent, and the use of apps for recruitment, diagnosis, follow-up, and treatment. Our second major objective of this conference series is the promotion of diversity in the biomedical workforce. It is well-known that the pipeline from training to full professor for women in biomedical research is leaky whereas the pipeline for under- represented minorities is practically non-existent. Drawing from national and local sources, we vet women and under-represented minorities for every invited speaker opportunity, thereby providing valuable career currency and networking opportunities. We will also encourage women and under-represented minorities, particularly at the trainee level, to attend and participate in this conference series to spur interest in pursuing genetics and genomics research as a career. Overall, the North Coast Conference on Precision Medicine series is a valuable addition to the national conference landscape, and with its unique location, low cost to participants, and travel awards, will serve as an important educational opportunity as precision medicine research accelerates in earnest.