Columbia University Minority/Underserved Site NCI Community Oncology Research Program
Columbia University Minority/Underserved Site NCI Community Oncology Research Program
批准号:
10456730
负责人:
Jennifer E. Amengual
金额:
$101.61万
依托单位国家:
美国
项目类别:
财政年份:
2014
资助国家:
美国
项目状态:
未结题
起止时间:
2014-08-01 至 2025-07-31
关键词:
Advisory CommitteesAgeCancer BurdenCancer CenterCancer ControlCancer PatientCatchment AreaClinical ResearchClinical TrialsClinical Trials NetworkCommunitiesCommunity Clinical Oncology ProgramCommunity HealthContinuity of Patient CareEnrollmentEthnic OriginGenderGoalsHealth PersonnelHerbert Irving Comprehensive Cancer CenterIndividualInfrastructureInstitutional Review BoardsLeadLeadershipMedical centerMinorityMinority GroupsMinority ParticipationPatientsPhasePopulationPreventionQuality of lifeRaceResearchRoleScreening for cancerSex OrientationSiteSocioeconomic StatusTherapeutic TrialsTissuesUniversitiesbasebiobankcancer carecancer clinical trialcancer preventioncancer therapycare deliverydesignhealth care disparityimprovednovel therapeuticsoutreachpatient populationprogramsscreeningunderserved communityunderserved minority
中文摘要
项目总结
赫伯特·欧文综合癌症中心的少数民族/服务不足的国家社区肿瘤学
哥伦比亚大学欧文医学中心的研究项目(HICCC/CUIMC/MU-NCORP)已经建立
一个强大的基础设施,便于识别、激活和参与NCORP研究基地
临床试验。HICCC/CUIMC/MU-NCORP的总体目标是为
围绕着我们的癌症中心的少数族裔/不应得的人群。我们节目的具体目标是:1)
为我们的患者社区和医疗保健提供者提供并增强对NCI临床产品组合的访问
试验网络(NCTN/NCORP)试验,特别是在癌症控制、癌症预防的四个组成部分
以及筛查、癌症护理(CCD)研究和癌症治疗(第一、第二、第三阶段)以及组织
收购;2)提高少数族裔和服务不足的患者参加这些试验的收益
试验组合的可获得性和可用性,以及确定和减少应计障碍以满足需求
领导、参与和推动NCORP/NCTN研究基地的癌症研究
护理连续体,特别关注减少医疗差距的研究,以及4)合作和
为NCI NCORP范围内的活动做出贡献。在过去的四年里,这种强大的基础设施导致了许多
成就。我们的MU-NCORP组合包括150多个试验,我们已经招募了500多名患者
到癌症控制和预防、癌症护理服务和治疗试验。我们一直超过
少数族裔和未得到充分服务的患者群体的最低30%应计目标。此外,我们已经采取了
在研究基地内发挥领导作用,并领导许多试验。通过促进注册和参与
少数人和服务不足的癌症患者进入高效果的临床试验,我们将实现我们的最终目标
提高所有个人的存活率和生活质量,不分年龄、种族、民族、性别、性取向
或社会经济地位。
英文摘要
PROJECT SUMMARY
The Herbert Irving Comprehensive Cancer Center’s Minority/Underserved National Community Oncology
Research Program at Columbia University Irving Medical Center (HICCC/CUIMC/MU-NCORP) has established
a robust infrastructure that facilitates the identification, activation and participation in NCORP Research Base
clinical trials. The overall goal of the HICCC/CUIMC/MU-NCORP is to provide the best in cancer care to the
minority/undeserved population that surrounds our cancer center. The specific aims of our program are to 1)
Provide and enhance access for our community of patients and healthcare providers to a portfolio of NCI Clinical
Trials Network (NCTN/NCORP) trials, specifically in the four components of cancer control, cancer prevention
and screening, cancer care delivery (CCD) research and cancer treatment (Phase I, II, III) as well as tissue
acquisition; 2) Enhance the accrual of minority and underserved patients onto these trials by promoting the
accessibility and availability of the trial portfolio and identifying and reducing accrual barriers to meet the needs
of our community, 3) Lead, participate, and promote NCORP/NCTN research base studies across the cancer
care continuum with a particular focus on studies that reduce healthcare disparities, and 4) Collaborate and
contribute to the NCI NCORP-wide activities. Over the past four years, this strong infrastructure has led to many
accomplishments. Our MU-NCORP portfolio consists of over 150 trials, and we have enrolled over 500 patients
to Cancer Control and Prevention, Cancer Care Delivery and Therapeutic Trials. We have consistently exceeded
the minimum 30% accrual target for minority and underserved patient populations. In addition, we have taken
leadership roles within the research bases and lead many trials. By facilitating the enrollment and participation of
minority and underserved cancer patients into high impactful clinical trials, we will achieve our ultimate goal of
improving survival and quality of life of all individuals regardless of age, race, ethnicity, gender, sexual orientation
or socioeconomic status.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Development of first-in-class histone acetyltransferase (HAT) activators for precision targeting of epigenetic derangements in lymphoma
-
批准号:10470919
-
项目类别:
-
资助金额:$37.06万
-
财政年份:2018
-
负责人:Jennifer E. Amengual
-
依托单位:
Development of first-in-class histone acetyltransferase (HAT) activators for precision targeting of epigenetic derangements in lymphoma
-
批准号:10241324
-
项目类别:
-
资助金额:$37.06万
-
财政年份:2018
-
负责人:Jennifer E. Amengual
-
依托单位:
Development of first-in-class histone acetyltransferase (HAT) activators for precision targeting of epigenetic derangements in lymphoma
-
批准号:9790953
-
项目类别:
-
资助金额:$35.95万
-
财政年份:2018
-
负责人:Jennifer E. Amengual
-
依托单位:
Columbia University Minority/Underserved Site NCI Community Oncology Research Program
-
批准号:10673181
-
项目类别:
-
资助金额:$102.1万
-
财政年份:2014
-
负责人:Jennifer E. Amengual
-
依托单位:
国内基金
海外基金
登录
查看更多内容
补阳还五汤通过AGE-RAGE通路调控脓毒症免疫失衡的机制与转化研究
-
批准号:JCZRLH202601523
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:
-
依托单位:
靶向递送一氧化碳调控AGE-RAGE级联反应促进糖尿病创面愈合研究
-
批准号:JCZRQN202500010
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2025
-
负责人:
-
依托单位:
对香豆酸抑制AGE-RAGE-Ang-1通路改善海马血管生成障碍发挥抗阿尔兹海默病作用
-
批准号:2025JJ70209
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2025
-
负责人:雷芬芳
-
依托单位:
AGE-RAGE通路调控慢性胰腺炎纤维化进程的作用及分子机制
-
批准号:--
-
项目类别:面上项目
-
资助金额:--
-
批准年份:2024
-
负责人:万荣
-
依托单位:
甜茶抑制AGE-RAGE通路增强突触可塑性改善小鼠抑郁样行为
-
批准号:2023JJ50274
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2023
-
负责人:贺志明
-
依托单位:
蒙药额尔敦-乌日勒基础方调控AGE-RAGE信号通路改善术后认知功能障碍研究
-
批准号:--
-
项目类别:地区科学基金项目
-
资助金额:33万元
-
批准年份:2022
-
负责人:都义日
-
依托单位:
补肾健脾祛瘀方调控AGE/RAGE信号通路在再生障碍性贫血骨髓间充质干细胞功能受损的作用与机制研究
-
批准号:--
-
项目类别:面上项目
-
资助金额:52万元
-
批准年份:2022
-
负责人:叶宝东
-
依托单位:
LncRNA GAS5在2型糖尿病动脉粥样硬化中对AGE-RAGE 信号通路上相关基因的调控作用及机制研究
-
批准号:
-
项目类别:省市级项目
-
资助金额:10.0万元
-
批准年份:2022
-
负责人:于海兵
-
依托单位:
围绕GLP1-Arginine-AGE/RAGE轴构建探针组学方法探索大柴胡汤异病同治的效应机制
-
批准号:81973577
-
项目类别:面上项目
-
资助金额:55.0万元
-
批准年份:2019
-
负责人:辛贵忠
-
依托单位:
AGE/RAGE通路microRNA编码基因多态性与2型糖尿病并发冠心病的关联研究
-
批准号:81602908
-
项目类别:青年科学基金项目
-
资助金额:18.0万元
-
批准年份:2016
-
负责人:刘括
-
依托单位: