Washington University Implementation Science Center for Cancer Control

项目摘要--总体构成部分 背景和愿景。作为一个高级中心，华盛顿大学实施的愿景 癌症控制科学中心(WU-ISCCC)正在进行实施研究，以帮助消除 农村和其他弱势社区的癌症差异。 进球了。WU-ISCCC的总体目标是为快速循环建立一个严谨的科学证据基础 提高有效癌症控制的可及性、外部有效性和可持续性的实施研究 干预措施。我们的目标和中心活动体现了三个不同的特点：(1)专注于消除癌症 差异；(2)需要进行快速周期研究；(3)使用系统科学方法来加强 实施科学中的方法和结果。 设置。我们的中心将位于一个特殊的环境中，以促进跨学科合作， 催生新想法，并确保支持为复杂实施找到解决方案的研究 在癌症差异很大的现实世界环境中的挑战(密苏里州和伊利诺伊州的农村和城市县)。 来自华盛顿大学的大量匹配捐款将使我们能够战略性地投资于新想法。 目标。该中心的具体目标是：(1)推进癌症控制的实施科学领域 通过进行创新和有影响力的研究；(2)扩大一支杰出的、多样化的实施团队 科学研究人员和利益攸关方；(3)组织和整合中心组件，以促进 跨学科团队科学；(4)建立一个实施实验室(称为“创新 孵化器“)作为创新、快速循环和有影响力的研究的渠道；和(5)解决癌症问题 通过使弱势群体尽可能容易地接触、使用和受益来实现差异 循证干预。 创新和影响。WU-ISCCC将具有创新性，并在科学上提供显著的回报 投资。首先，我们的中心有独特的特点，包括联合关注癌症差异， 应用战略进行快速循环研究，并使用系统科学方法。第二, 我们已经组建了一支多元化的世界级团队，与多个练习环境建立了牢固的联系，这些环境将 我们创新孵化器的关键部件。第三，我们将聘请不同学科的调查人员，并 投资发展早期职业学者，成为癌症实施科学家。第四，我们将 战略性地、创造性地传播产品，使研究人员、从业者和 社区成员。第五，我们为我们的项目制定了有针对性的集体整合战略， 核心和单元，以确保WU-ISCCC的影响大于其各个部分的总和。在……里面 总结，WU-ISCCC将成为促进消除贫穷实施科学的全国性资源 癌症差异。

PROJECT SUMMARY – Overall Component Background and vision. As an Advanced Center, the vision of the Washington University Implementation Science Center for Cancer Control (WU-ISCCC) is to conduct implementation research to help eliminate cancer disparities in rural and other disadvantaged communities. Goal. The overall goal of the WU-ISCCC is to build a rigorous, scientific evidence base for rapid-cycle implementation research to increase the reach, external validity, and sustainability of effective cancer control interventions. Our goal and Center activities capture three distinct features: (1) a focus on elimination of cancer disparities; (2) the need for rapid-cycle studies; and (3) the use of systems science approaches to enhance methods and outcomes in implementation science. Setting. Our Center will be housed in an exceptional environment that fosters transdisciplinary collaboration, catalyzes new ideas, and ensures support for research that finds solutions for complex implementation challenges in real-world settings with high cancer disparities (rural and urban counties in Missouri and Illinois). Substantial matching contributions from Washington University will allow us to strategically invest in new ideas. Aims. The specific aims of the Center are to: (1) advance the field of implementation science in cancer control by conducting innovative and impactful research; (2) expand an exceptional, diverse team of implementation science investigators and stakeholders; (3) organize and integrate Center components to facilitate transdisciplinary team science; (4) develop an Implementation Laboratory (known as the “Innovation Incubator”) to serve as a conduit for innovative, rapid-cycle, and impactful research; and (5) address cancer disparities by making it as easy as possible for disadvantaged populations to encounter, use, and benefit from evidence-based interventions. Innovations and impact. The WU-ISCCC will be innovative and provide a significant return on the scientific investment. First, our Center has distinctive features that include a combined focus on cancer disparities, the application of strategies to conduct rapid-cycle studies, and the use of systems science approaches. Second, we have assembled a diverse, world class team with strong linkages to multiple practice settings that will be critical parts of our Innovation Incubator. Third, we will engage investigators from different disciplines and invest in the development of early career scholars as cancer implementation scientists. Fourth, we will strategically and creatively disseminate products in ways that will benefit researchers, practitioners, and community members. Fifth, we have developed a focused strategy for collective integration of our projects, cores, and units to ensure that the WU-ISCCC impact is greater than the sum of its individual parts. In summary, the WU-ISCCC will be a national resource for furthering implementation science for eliminating cancer disparities.