Multi-Disciplinary Training grant in Cancer Research

计划摘要 越来越多的新技术和新学科被应用于翻译中的挑战 将基础癌症研究成果转化为有意义的临床结果。多学科交叉 癌症研究培训基金(MTCR)是一项既定的博士前培训计划，网址为 芝加哥大学由美国国立卫生研究院/美国国立卫生研究院T32-009594支持，旨在提供严格的 为研究生提供培训和相关经验，他们将成为下一代 癌症研究的领导者和先驱。MTCR的核心使命是培训我们最多的 有才华的博士后学生剖析和设计将癌症视为一种疾病的新方法， 无论是通过更好地理解 癌症的发生和发展，开发监测和调节癌细胞的新工具 对治疗干预的反应，或利用关于人类癌症的更多信息 识别最脆弱的癌症途径的数据集和新的计算方法。 MTCR领导层在2014年进行了一项战略审查，结果重新调整了 计划目标是使为癌症研究预科学生提供的培训现代化 芝加哥大学。通过更严格的师资培训人员遴选和引入新的 翻译癌症研究、化学生物学、分子方面的课程和培训内容 工程和计算方法，MTCR计划提供的培训是多- 并强调以问题为基础的学习和实践经验。MTCR还 通过MyChoice计划和Polsky促进职业发展机会 我们的实习生所在的芝加哥大学创业与创新中心 通过研讨会、研讨会和实习接触到与职业相关的技能 生物技术、科学新闻和其他研究密集型职业。我们还有 制定了更有效的机制来招收不同背景的学生 通过部署现有学员和我们的校友网络，结合更多 招聘的整体规则。由于过去所有这些不同的计划变化 周期，我们的计划表现出提高了生产力，缩短了毕业时间，改善了 培训成果，包括出版物、奖学金和学员参加培训的百分比 研究密集型和与研究相关的职业。在接下来的5年里，有了新的资金， 我们的目标是建立在我们成功的培训方法的基础上，最终目标是确保 下一代癌症研究人员拥有知识、技能和工具来制造 对我们这个时代消除癌症死亡这一集体目标产生重大影响。

Program Summary Increasingly, new technologies and disciplines are being applied to challenges in translating fundamental cancer research findings into meaningful clinical outcomes. The Multi-disciplinary Training grant in Cancer Research (MTCR) is an established pre-doctoral training program at the University of Chicago supported by NIH/NCI T32-009594 that seeks to provide rigorous training and relevant experience to graduate students who will make up the next generation of cancer research leaders and pioneers. The core mission of the MTCR is to train our most talented pre-doctoral students to dissect and design new ways of attacking cancer as a disease, whether that be through achieving a better understanding of the mechanistic underpinnings of cancer initiation and progression, developing novel tools to monitor and modulate cancer cell responses to therapeutic intervention, or to exploit increased information about human cancer datasets and new computational methods to identify the most vulnerable cancer pathways. MTCR leadership carried out a strategic review in 2014 resulting in a re-alignment of programmatic goals to modernize training provided to pre-doctoral cancer research students at UChicago. Through more stringent selection of faculty trainers and introduction of new coursework and training elements in translational cancer research, chemical biology, molecular engineering and computational approaches, the MTCR program provides training that is multi- disciplinary and emphasizes problem-based learning and hands-on experience. The MTCR also promotes career development opportunities through the MyCHOICE program and the Polsky Center for Entrepreneurship & Innovation at the University of Chicago where our trainees are exposed through seminars, workshops and internships to skills relevant to a career in biotechnology, science journalism and other research-intensive careers. We have also developed more effective mechanisms for recruitment of students from diverse backgrounds through deployment of current trainees and our alumni network, in combination with more holistic rubrics for recruitment. As a result of all these various program changes in the past cycle, our program has shown enhanced productivity with reduced time to graduation, improved training outcomes in terms of publications, fellowship awards and percent trainees going into research-intensive and research-related careers. Over the next 5 years with renewed funding, we aim to build on our successful training approaches, with the ultimate goal of ensuring that the next generation of cancer researchers have the knowledge, skills and tools to make a meaningful impact on the collective goal of eliminating cancer deaths in our time.