Pilot and Feasibility

摘要/总结-P/F程序 MNORC试点和可行性赠款计划（P & F）的主要目标是促进 研究肥胖的生物和行为决定因素，改变 改变代谢和调节疾病风险的营养成分和量， 制定干预措施，以减少肥胖及其疾病后遗症，使用基础，临床，或 人口接近。为了实现这一目标，我们为新的和 密歇根大学的研究人员建立了足够的初步信息， 成功申请NIH或其他国家拨款的重大研究资金 社. MNORC P & F赠款计划每年10万美元的资金主要来自成本- 密歇根大学内的几个学校提供的共享，目前在 在第二轮融资中。每项计划均会发放两至三项标准资助， 尽管该计划只完成了两个融资周期，但这笔投资已经完成了 导致了相当大的回报发表论文，资助NIH赠款，和合作 其他MNORC成员。除了目前提供的P & F赠款外，P & F计划 将在下一个周期扩大到包括与密歇根糖尿病基金会资助的共享赠款 研究中心和陶布曼中心的共同研究兴趣。

Abstract/Summary – P/F Program The primary goal of the MNORC Pilot and Feasibility Grants Program (P&F) is to promote research on the biological and behavioral determinants of obesity, the effects of altered composition and quantity of nutrients to alter metabolism and modulate disease risk, and to develop interventions to reduce obesity and its disease sequelae using basic, clinical, or population approaches. To achieve this goal, we provide opportunities for both new and established University of Michigan investigators to generate sufficient preliminary information for a successful application for major research funding from NIH or other national granting agencies. The $100K/year for the MNORC P&F grants program is largely funded from cost- sharing provided by several Schools within the University of Michigan, and is currently in the midst of its second cycle of funding. Two to three standard grants have been given out each year, and despite that the program has only completed two funding cycles, this investment has resulted in a considerable return of published papers, funded NIH grants, and collaborations with other MNORC members. In addition to the P&F grants currently provided, the P&F program will expand over the next cycle to include shared grants funded with the Michigan Diabetes Research Center and the Taubman Center for common research interests.