Interdisciplinary Training in Rheumatic Diseases

项目摘要 此更新申请寻求对T-32，风湿性关节炎跨学科培训的持续支持 疾病在范德比尔特大学。该计划寻求2个博士前和3个博士后职位的支持。 该计划的目标是为下一代调查人员提供必要的工具， 关键发现，并促进我们对复杂风湿性疾病的理解和治疗。我们 教师创造了一个发现的互动环境，桥梁临床和基础研究， 博士前和博士后学员。跨学科的方法与精心策划的指导相结合 过程，使受训人员有广阔的视野，他们接触到的机会， 临床翻译的问题，不能解决一个单一的实验室。该计划中的导师是 高度互动，并在研究小组之间保持广泛的合作努力。这些 互动在项目内创建了四个兴趣小组：先天性和适应性免疫;血管生物学 和炎症;精准医学;和肌肉骨骼生物学。该计划是为了满足 个人的职业目标谁想要应用先进的技术，如基因组学或蛋白质组学， 风湿性疾病，以及支持个人的职业生涯谁想要把这些进步， 改善医疗保健。除了部门和导师特定的实验室指导外， 通过跨学科课程接受风湿病研究培训。综合研究 论坛、期刊俱乐部和共享核心设施促进了各个实验室或部门以外的互动。 在该计划的学员积极指导教师和通过“同行指导”， 以前的学生和高级研究员在该计划。MSCI和MPH的学位授予途径将 提供给节目。对该司的设施进行了大量机构投资， 优秀的新教师进一步加强了未来的计划。

PROJECT SUMMARY This renewal application seeks continued support for the T-32, Interdisciplinary Training in Rheumatic Diseases at Vanderbilt University. The program seeks support for 2 predoctoral and 3 postdoctoral positions. The goal of the program is to provide the next generation of investigators with the tools necessary to make critical discoveries and to advance our understanding and treatment of complex rheumatic disorders. Our faculty have created an interactive environment of discovery that bridges both clinical and basic research for pre and post-doctoral trainees. An interdisciplinary approach is coupled with a carefully orchestrated mentoring process so that trainees are provided with a broad perspective and they are exposed to opportunities for clinical translation of problems that cannot be solved by a single laboratory. The preceptors in the program are highly interactive and maintain extensive collaborative efforts between and among the research groups. These interactions create four Interest Groups within the program: Innate and Adaptive Immunity; Vascular Biology and Inflammation; Precision Medicine; and Musculoskeletal Biology. The program is organized to meet the career goals of individuals who want to apply advanced technologies, such as genomics or proteomics to rheumatic disease as well as to support the careers of individuals who want to translate these advances to improve health care. In addition to Departmental and preceptor-specific laboratory instruction, each trainee receives rheumatic disease research training through an interdisciplinary curriculum. Combined research forums, journal clubs and shared core facilities promote interactions beyond individual laboratories or divisions. Trainees in the program are actively mentored by both faculty members and through “peer mentoring” by former students and senior fellows in the program. Degree granting pathways for MSCI and MPH will be available to the program. Significant institutional investment in the Division's facilities and the recruitment of outstanding new faculty further strengthen the program for the future.