Pilot Core

项目摘要-试点核心 康奈尔罗伊巴尔中心拟议的试点核心-稍后成立的疼痛翻译研究所 LIFE(TRIPLL)将维持和延长TRIPLL的试点和调查员开发计划的战略 在过去的5年里取得了显著的成功。我们建议促进翻译研究 关于晚年生活中的疼痛的活动，导致开发基于 行为改变科学(SOBC)使用NIH阶段模型指导干预发展和 在翻译管道上取得进展。康奈尔大学的罗伊巴尔中心将专注于翻译研究 关于代表性不足的人群，即有认知障碍的老年人、少数族裔老年人、老年人 生活在农村地区，以及艾滋病毒携带者的成年人。考虑到不成比例的撞击性疼痛，这种关注是适当的 对这些人群产生了影响。TRIPLL的Pilot Core将汇集其 管理核心、研讨会和教育举措，以实现其确保持续增长的目标 和发展受训者的研究独立性，确保及时的项目进展和研究 诚信，开发有效和可扩展的行为干预措施，确保将研究结果传播到 适当的受众，培养指导人员的资质，并提供远远超出 完成试点研究。康奈尔·罗伊巴尔中心的首要目标是传播行为 可衡量地改善受疼痛影响的老年人的健康和福祉的干预措施。在……里面 拟议的延续，康奈尔大学试点核心的具体目标是： 1)培养对翻译社会和行为科学研究的兴趣和职业承诺 晚年痛苦背景下的行为改变；2)基金与研究主题相关的创新先导研究 中心(疼痛应对和管理)，与NIH阶段干预模式一致 行为改变科学中的发展和理论原则的驱动；3)导师试点受赠者 在进行翻译研究时，4)通过以下方法监督研究人员的发展计划 在与NIH阶段一致的干预开发中进行转译研究并提供指导 模型，以及5)进一步发展支持行为干预的翻译研究的能力 跨协作站点的开发。 TRIPLL的试点核心的目标意义重大，因为行为改变干预最终将是 如果清楚地了解了驱动行为变化的潜在机制，那么这种方法就会更有效。最后，三相锁相环 试点研究将利用社会科学/行为科学的新理论创新来提高疗效， 在受疼痛影响的老龄人口中实施的干预措施的有效性和传播。

Project Summary – Pilot Core The proposed Pilot Core of Cornell’s Roybal Center–The Translational Research Institute on Pain in Later Life (TRIPLL) will maintain and extend the strategies TRIPLL’s pilot and investigator development program employed over the past 5 years to achieve measurable success. We propose to foster translational research activities on pain in later life that lead to the development of potent and scalable interventions based in the science of behavior change (SOBC) using the NIH Stage Model to guide intervention development and progression along the translational pipeline. Cornell’s Roybal Center will focus its translational research efforts on underrepresented populations, i.e., older adults with cognitive impairment, minority elders, older adults living in rural areas, and adults aging with HIV. This focus is appropriate given the disproportionate impact pain has on these populations. TRIPLL’s Pilot Core will bring together methodological leadership from its Management Core, seminars and educational initiatives to achieve its goals of assuring the continued growth and development of mentees towards research independence, ensuring timely project progress and research integrity, developing potent and scalable behavioral interventions, assuring dissemination of research results to appropriate audiences, developing mentee grantsmanship, and providing continued support well beyond completion of the pilot study. Cornell Roybal Center’s overarching goal is to disseminate behavioral interventions that measurably improve the health and well-being of aging adults adversely affected by pain. In the proposed continuation, the specific aims of Cornell’s Pilot Core are to: 1) Foster interest in and career commitment to translating research on the social and behavioral science of behavior change in the context of later-life pain; 2) Fund innovative pilot studies related to the research theme of the center (Pain Coping and Management), consistent with the NIH Stage Model of Intervention Development and driven by theoretical principles in the Science of Behavior Change; 3) Mentor pilot grantees in conducting translational research, 4) Supervise a program of investigator development in the methods of translational research and provide mentorship in intervention development consistent with the NIH Stage Model, and 5) Develop further the capacity for supporting translational research on behavioral intervention development across collaborating sites. The aims of TRIPLL’s Pilot Core are significant because behavior change interventions will ultimately be more effective if the underlying mechanisms driving behavior change are clearly understood. Finally, TRIPLL pilot studies will leverage new theoretical innovations in the social/behavioral sciences to improve the efficacy, effectiveness, and dissemination of interventions implemented in aging populations adversely affected by pain.