Core A: Administrative and Biostatistics Core

项目摘要-管理和生物统计学核心（核心A） 行政和生物统计核心（核心A）的总体目标是：1）继续提供一个结构， 促进实现本计划项目目标的有效互动，特别是 促进和促进该计划的目标和每个组成部分（核心和项目），通过提供科学的 指导，行政和预算支持，监督，计划活动和工业的整合 合作伙伴，并确保运营效率;和2）继续提供生物统计和其他统计数据， 支持P01。核心A的目标如下：1）通过设定 研究议程侧重于从选定的热带雨林植物中发现新的化学物质，以及 地衣、蓝细菌和丝状真菌，用于开发作为癌症化疗剂， 目前的治疗方法无法治愈的肿瘤。2)确保计划组件的运营效率 通过提供集中的赠款管理、信息传播、预算数据处理和交换， 信息和服务。3)促进研究项目和核心的整合，以促进互动 在调查者代表的三所主要大学和相关外部实体中， 为P01计划的三个项目和两个核心提供生物统计学支持。核心A将继续 以确保该计划的所有组成部分无缝地协同工作，以完成整体和具体的 P01计划的目标。

PROJECT SUMMARY – ADMINISTRATIVE AND BIOSTATISTICS CORE (CORE A) The overall goals of the Administrative and Biostatistics Core (Core A) are to 1) continue to provide a structure to facilitate effective interactions toward the accomplishment of the aims of this Program Project and specifically to foster and promote the goals of the Program and each component (cores and projects) by providing scientific direction, administrative and budgetary support, oversight, integration of program activities and the industrial partner, and ensuring operational efficiency; and 2) to continue to provide biostatistics and other statistical support for the P01. The following are the objectives of Core A: 1) provide research direction by setting the research agenda focused on the discovery of novel chemicals from selected tropical rainforest plants, as well as lichens, cyanobacteria and filamentous fungi, for development as cancer chemotherapeutic agents, particularly for tumors not cured by present treatment methods. 2) Ensure operational efficiency for Program components by providing centralized grant administration, information dissemination, budget data processing, and exchange of information and services. 3) Promote integration of the Research Projects and Cores to promote interaction among the three primary universities represented by the investigators, and relevant external entities and 4) provide biostatistics support for the three Projects and the two Cores of the P01 Program. Core A will continue to ensure that all components of the Program work seamlessly together to accomplish the overall and specific project goals of the P01 Program.