Integrative and translational training in pain research

描述(由申请人提供)： 未来在疼痛研究和疼痛管理方面的战略可能会从临床医生和基础研究人员的合作努力中演变出来，以确定新的治疗靶点，以及对急性和慢性疼痛的发生和发展负责的贡献和预测因素。实现这一目标将需要多学科和跨学科的方法，利用最先进的资源，以及接受过培训的个人来理解疼痛体验的生物和心理社会组成部分的复杂性。拟议的培训计划的设计纳入了实现这些目标的战略，利用不同的背景和得到强有力的机构承诺支持的核心培训教师小组的有据可查的专业知识，以及为受训人员在疼痛研究领域的职业生涯做准备的合作环境。该计划在代表核心教员研究兴趣的五个指定领域提供培训机会。努力的重点将是招募杰出的科学家和临床医生，与健康科学中心和麦克奈特脑研究所的导师合作。位于整个医疗中心的临床设施将用于为培训计划提供临床部分。受训者将接受一项全面的计划，该计划包括：(A)教学和研究部分，以及(B)要求参与临床和基础研究轮换。该方案包括：(A)一个平衡良好的核心课程；(B)关于招募人数不足的少数族裔的规定；(C)涉及研究道德行为的必要组成部分；以及(D)确保该方案满足受训者在研究、教育和专业发展领域的需求的步骤。由于慢性疼痛的发病率不断上升，再加上疼痛管理的惊人成本，因此需要为下一代疼痛研究人员制定新的培训策略。佛罗里达大学疼痛研究界认识到这一挑战，并在现有和不断扩大的教育和研究资源的基础上，致力于培养疼痛专家，这些专家将有助于改善对急性和慢性疼痛的理解和临床管理。该计划的目标是培养有能力开发临床和/或基础科学研究计划的个人，并向这些个人灌输对协作、多学科计划在应对疼痛研究领域当前和未来挑战方面的好处的欣赏。

DESCRIPTION (provided by applicant): Future strategies in pain research and pain management will likely evolve from the collaborative efforts of clinicians and basic researchers working in partnership to identify novel therapeutic targets, along with contributing and predictive factors responsible for the onset and progression of acute and chronic pain. Accomplishing this goal will require multidisciplinary and interdisciplinary approaches utilizing state-of-the art resources along with individuals trained to appreciate the complexities of the biological and psychosocial components of the pain experience. The design of the proposed training program incorporates strategies to accomplish these goals utilizing the diverse backgrounds and well-documented expertise of a core group of training faculty backed by a strong institutional commitment, and a collaborative environment to prepare trainees for careers in pain research. The program offers training opportunities in five designated tracts that represent the research interests of the core faculty. Efforts will focus on recruiting outstanding scientists and clinicians to work with mentors found within the Health Science Center and the McKnight Brain Institute. Clinical facilities located throughout the Medical Center will be used to provide a clinical component to the training program. Trainees will be exposed to a comprehensive program that consists of: (a) didactic and research components as well as (b) required participation in clinical and basic research rotations. The program contains: (a) a well balanced core curriculum; (b) provisions for the recruitment of underrepresented minorities; (c) a required component dealing with the ethical conduct of research; and (d) steps to ensure the program meets the needs of trainees in areas of research, education, and professional development. Due to the escalating prevalence of chronic pain conditions, combined with the staggering cost of pain management, there is a need for novel training strategies for the next generation of pain researchers. The University of Florida pain research community recognizes this challenge and with existing and expanding resources in education and research, there is a commitment to produce pain specialists that will contribute to the improved understanding and clinical management of acute and chronic pain. The goal of the program is to produce individuals equipped to develop clinical and/or basic science research programs and to instill in these individuals an appreciation for the benefits of collaborative, multidisciplinary programs in meeting the present and future challenges in the field of pain research.