ARTHRITIS AND IMMUNOLOGY

描述（由申请人提供）：风湿病和免疫学研究培训计划的主要目标是：a)为学员提供风湿病研究基础的实验室和/或非实验室研究的广泛研究经验；b)培养学员的调查技能发展。该项目面向对疾病导向研究感兴趣并致力于风湿病基础和/或临床研究的博士生、医学博士和博士。学员将在风湿病的分子和细胞机制和/或流行病学方面获得扎实的背景知识，并有资格从事风湿病学和免疫学研究方面的独立调查。受训者可以在瑟斯顿关节炎研究中心（TARC）选择不同的教师作为导师。所有的导师都有充足的资金来进行他们的研究。培养计划在风湿病学学术领域发展的医学博士博士后是重点。还作出特别努力，征聘少数民族候选人。培训计划主要是指导性的，75%以上的学员时间用于独立研究活动，辅以结构化的教学。正在进行的动物和人类生物医学研究涵盖了许多与自身免疫、关节炎和肌肉骨骼疾病相关的问题。实习实验室研究由所有必要的设备和资源支持现代分子和细胞免疫学，基因组学，蛋白质组学和细胞生物学。非实验室研究的机会来自TARC内的多学科临床研究中心的多种资源以及北卡罗来纳大学健康科学校园的其他资源。微生物/免疫学系、生物化学与生物物理系、医学院其他系、流行病学、健康行为与健康教育系、公共卫生学院其他系全部课程面向学员开放。学员必须参加各种研讨会和会议，包括每周一次的研究进展会议，学员在会上介绍他们的研究和负责任的研究行为。博士预科学员的课程是根据他们的需求量身定制的，包括与他们的学位课程相关的正式教学，以及我们培训计划结构中的其他课程。鼓励博士后学员获得NIH K08， K23， R01和R03系列奖励和关节炎基金会等校外资助，并充分利用这些机会进入学术生涯。在过去的10年里，该项目的大部分博士生（24人中的24人，100%）和博士后（44人中的39人，89%）都以实习生、大学教师或行业研究人员的身份从事学术工作。

DESCRIPTION (provided by applicant): The primary goals of this Rheumatology and Immunology Research Training Program are: a) to provide trainees with a broad investigational experience in laboratory and/or non-laboratory research basic to the study of rheumatic diseases and b) to foster the development of investigative skills in trainees. The program is open to pre-doctoral students, MDs and PhDs interested in disease oriented research and committed to a career in basic and/or clinical research in rheumatic diseases. Trainees will develop a solid background in the molecular and cellular mechanisms of and/or epidemiology of rheumatic diseases and become qualified to embark upon their careers as independent investigators in rheumatology and immunology research. Trainees may select a diverse faculty in the Thurston Arthritis Research Center (TARC) as mentors. All of the mentors are well funded to conduct their research. The training of MD postdoctoral fellows who plan careers in academic rheumatology receives major emphasis. Special efforts are also made to recruit minority candidates. The training program is largely preceptorial, with more than 75% of the trainee's time devoted to independent research activities, supplemented with structured didactics. Ongoing animal and human biomedical research encompasses many of the issues relevant to autoimmunity, arthritis, and musculoskeletal disease. Trainee laboratory research is supported by all of the necessary equipment and resources for modern molecular and cellular immunology, genomics, proteomics, and cell biology. Opportunities in non-laboratory investigation derive from the multiple resources of the Multidisciplinary Clinical Research Center within the TARC and other resources throughout the UNC health sciences campus. The entire curriculum in the Departments of Microbiology/Immunology, Biochemistry and Biophysics, other School of Medicine departments, Epidemiology, Health Behavior & Health Education, and other departments in the School of Public Health are open to trainees. Trainees are required to participate in a variety of seminars and conferences, including a weekly research-in-progress conference where trainees present their research and those dealing with responsible conduct of research. The curriculum for pre-doctoral trainees is tailored to their needs and consists of formal didactics relative to their degree program, as well as others within the structure of our training program. Post-doctoral trainees are encouraged to obtain extramural funding such as NIH K08, K23, R01, and R03 series awards and Arthritis Foundation and to parlay those opportunities into academic careers. The majority of pre- (24 of 24, 100%) and post-doctoral (39 of 44, 89%) trainees in this program over the last 10 years are currently engaged in academic endeavors as trainees, university faculty or industry researchers.