Linking Parent Drug Use and Child Development Across Three Generations

描述（由申请人提供）：这是一项旨在检查父母和祖父母使用药物对儿童和青少年发育的影响和作用机制的申请。我们寻求5年的支持，以收集和分析有关西雅图社会发展项目（SSDP）小组成员的儿童的数据。SSDP（J.大卫霍金斯，PI）是一个理论驱动的研究，在其早期嵌套预防干预。代际项目（TIP，卡尔G。希尔，PI）研究了SSDP成员的第一个孩子，SSDP G2父母自己，以及他们的伴侣。早期的工作集中在父母吸毒对儿童的影响。我们提出了一项后续研究，以扩大数据收集和分析的额外三波大多数G3儿童过渡到青春期。这将提供足够的样本量，以检查1）既往和当前父母和祖父母药物使用对发育和药物使用开始的影响，2）既往和当前父母和祖父母药物使用可能影响儿童发育和药物使用开始的机制，3）G2在儿童时期所经历的预防性干预的受益程度影响G3的发展环境、G2的父母教养方式和G3的发展成果。这项研究建立在现有的20年纵向研究的基础上，并将与其延伸到30年代的研究平行进行，没有科学或预算重叠。这项拟议的研究提供了一个独特的机会，可以检查三代人之间的吸毒因素，并分析G2在青春期和成年早期吸毒对他们的养育行为和孩子的结果的影响。研究结果将促进对青少年和成年早期父母和祖父母吸毒对儿童发育、行为和吸毒开始的影响的理解，并将为旨在打破吸毒代际传播周期的预防性干预措施的设计提供具体目标。 公共卫生相关性：这项研究将促进对青少年和成年早期父母和祖父母吸毒对儿童发育、行为和开始吸毒的影响的了解，并将为旨在打破吸毒代际传播周期的预防性干预措施的设计提供具体目标。

DESCRIPTION (provided by applicant): This is an application to examine the effects and mechanisms of action of parental and grandparental drug use on child and adolescent development. We seek 5 years of support to collect and analyze data on the children of the members of the Seattle Social Development Project (SSDP) panel. SSDP (J. David Hawkins, PI) is a theory-driven study with a preventive intervention nested within its early years. The Intergenerational Project (TIP, Karl G. Hill, PI) has studied the firstborn children of SSDP members, the SSDP G2 parents themselves, and their partners. Earlier work focused on effects of parent drug use on children. We propose a follow-up study to extend data collection and analysis for an additional three waves as most G3 children transition into adolescence. This will provide adequate sample sizes for examination of 1) the impact of prior and current parental and grandparental drug use on development and drug use initiation, 2) mechanisms through which prior and current parental and grandparental drug use may affect child development and drug use initiation, and 3) the degree to which benefits from preventive intervention experienced by G2 when they were children affect G3's developmental environment, G2's parenting practices, and G3's developmental outcomes. The study builds on an existing 20-year longitudinal study, and will run parallel to its extension into the 30's, without scientific or budgetary overlap. The proposed study presents a unique opportunity to examine factors linking drug use across three generations and to analyze the effects of G2's drug use during adolescence and early adulthood on their parenting behaviors and on their children's outcomes. Study findings will advance understanding of the effects of parental and grandparental drug use during adolescence and early adulthood on children's development, behavior, and drug use initiation and will provide specific targets for the design of preventive interventions aimed at breaking cycles of intergenerational transmission of drug use. PUBLIC HEALTH RELEVANCE: The study will advance understanding of the effects of parental and grandparental drug use during adolescence and early adulthood on children's development, behavior, and drug use initiation and will provide specific targets for the design of preventive interventions aimed at breaking cycles of intergenerational transmission of drug use.