Planning Grant for Global Infectious Disease Research Training Program

描述(申请人提供)：结核病，包括多药耐药(MDR-TB)和广泛耐药(XDR-TB)形式，仍然是一个全球公共卫生问题，目前日益增长的人类免疫缺陷病毒(HIV)疫情加剧了这一问题。世界结核病负担主要来自亚洲中低收入国家，特别是中国、印度和东南亚的农村地区，与其社会经济地位低、可获得性差和卫生保健系统薄弱有关。人力资源不足和服务效率低下延误了控制进程。宋卡亲王大学(EPI-PSU)流行病学股、世界卫生组织(WHO)在泰国确定的研究指导机构和合作机构建议建立一个针对这些亚洲受影响地区结核病的全球传染病培训计划(GID)。EPI-PSU一直在越南、缅甸、印度尼西亚、中国和尼泊尔的中心提供援助。拟议的结核病研究培训方案的长期目标是发展伙伴机构在LMICs的研究能力，衡量标准是在5年内提高接受培训并重返工作岗位的研究人员和国际出版物的资质。这笔D71拨款将用于规划培训计划。具体目标是确定亚洲低中等收入国家潜在结核病研究中心对研究和研究培训的需求、优先事项和可行性，为该地区的结核病国际培训方案制定计划，并建立一种机制，以确保研究和研究培训活动将朝着正确的方向进行，具有高生产力和高效率，并与所确定的需求相关。为实现这些目标，计划免疫研究所将首先选择与该地区的结核病研究人员和研究机构合作的战略伙伴机构，并形成一个网络。该网络中的合作中心将举行会议，介绍和讨论研究所概况、结核病研究培训的需求和优先领域，以及确保受训者在培训期间和返回国内研究所后工作良好的机制。到年底的时候 在12个月期间，目标学员机构将有与培训有关的目标和目的、统一的参与者遴选程序、潜在研究主题清单、培训时间表和议程、监测和评价计划以及东道国准备的材料。 公共卫生相关性：结核病(TB)是一种致命的空气传播传染病。泰国是一个结核病负担高的例外国家，但结核病控制的研究能力相对先进。Songkla亲王大学流行病学部、Siriraj医院医学院微生物学系和理学院微生物系是结核病流行病学和卫生系统研究以及基础科学研究方面的杰出中心。它们组成了一个小组，提交一份关于加强它们在亚洲其他中低收入国家机构发展研究能力的能力的提案。研究能力的提高最终将提高这些国家疾病控制方案的效率，进而减轻世界结核病负担。

DESCRIPTION (provided by applicant): Tuberculosis (TB), including the multi-drug resistant (MDR-TB) and extensively drug resistant (XDR-TB) forms continues to be a global public health problem, escalated by the current growing human immunodeficiency virus (HIV) epidemic. Associated with low socio-economic status, poor accessibility to care and weakness in health care systems, the majority of world TB burden comes from low and medium income countries (LMIC) of Asia, especially rural parts of China, India, and Southeast Asia. Inadequate human resources and inefficient services have delayed the control process. The Epidemiology Unit, Prince of Songkla University (EPI-PSU), a World Health Organization (WHO) identified research mentoring institute in Thailand and collaborating institutions proposes to establish a Global Infectious Disease Training Program (GID) targeted at TB in these Asian affected regions. EPI-PSU has been assisting centers in Vietnam, Myanmar, Indonesia, China and Nepal. The long-term objective of the proposed tuberculosis research training program is to develop research capacity of the partner institutes in LMICs, judged by improved qualification of their research staff who have been trained and returned to work and international publications out of the collaborative research in a 5-year period. This D71 grant will be used to plan the training program. Specific objectives are to identify the needs for and priority and feasibility of research and research training in potential research centers in Asian LMICs regarding tuberculosis, to achieve a plan for the international training program on tuberculosis for the region, and to set up a mechanism to ensure that the activities on research and research training will be executed in a right direction, with high productivity and efficiency and relevance to the needs so identified. To achieve the objectives, EPI-PSU will begin by choosing strategic partner institutes to work with and forming a network of TB researchers and research institutes in the region. The collaborating centers in this network will meet to present and discuss institute profiles, needs and priority areas of TB research training, mechanisms to ensure that the trainees will be working well during the training and after returning to home institutes. By the end of the 12-month period, target trainee institutions will have goals and objectives in relation to training, a uniform participant selection process, a list of potential research topics, training schedule and agenda, monitoring and evaluation plans, and prepared materials by the host. PUBLIC HEALTH RELEVANCE: Tuberculosis (TB) is a deadly airborne infectious disease. Thailand is an exception country where TB burden is high, yet the research capacity for TB control is relatively advanced. The Epidemiology Unit, Prince of Songkla University, and the Departments of Microbiology at Faculty of Medicine Siriraj Hospital and of Faculty of Science are centers of excellence in epidemiology and health systems research and basic science research on TB. They have formed a team to submit a proposal concerning enhancing their capacity to develop research capacity in institutions of other low and medium income countries (LMIC) in Asia. Increase in research capacity would eventually improve efficiency of the disease control programs in those countries and in turn reduce the world TB burden.