Research Support Core C: Functional Genomics and Bioinformatics Core

功能基因组学和生物信息学核心实验室(FGBCL)的长期目标是以经济高效的方式提供各种基于基因组学的分析、基本蛋白质组测量和生物信息学分析，从而最大限度地提高这些重要工具的可用性，供所有五名UW SBRP研究人员使用。FGBCL将提供基于微阵列的以基因为中心的转录表达分析(使用Affymetrix阵列和/或NimbleGen阵列)、基于ELISA的测量、定量基因表达评估以及数据的生物信息学分析，包括topGO重量法、基因集分析和PAINT。FGBCL为四名研究人员(DRS Furlong、Checkoway、Zhang和Gallagher)提供的服务将通过以下方式支持特定的生物医学研究目标

The long term objective of the Functional Genomics and Bioinformatics Core Laboratory (FGBCL) is to provide a variety of genomics-based assays, basic proteomic measurements, and bioinformatic analyses in a cost-effective and efficient manner, therefore maximizing the availability of these important tools for all five individual UW SBRP investigators. The FGBCL will furnish microarray-based gene-centric transcript expression analysis (using Affymetrix arrays and/or NimbleGen arrays), ELISA-based measurements, quantitative gene expression evaluations, and bioinformatic analyses of data including the topGO weight method, gene set analysis, and PAINT. The FGBCL services to four investigators (Drs Furlong, Checkoway, Zhang, and Gallagher) will support the specific Biomedical Research objective through