Peru Infectious Diseases Epidemiology Research Training Consortium

描述(由申请人提供)：当前的流感大流行明显表明，在对新出现的传染病的知识和应对能力方面存在差距。在我们奖项的第一阶段，“秘鲁传染病流行病学研究培训联盟”，NMRCD-UPCH-JHBSPH-USUHS联盟为秘鲁可持续研究能力的建设做出了贡献。两名硕士毕业生和一名博士生返回秘鲁，正在研究大流行和季节性流感的关键流行病学和生态学方面，三名受训人员即将完成课程。此外，我们在秘鲁建立了一个近乎自给自足的、由学费资助的流行病学硕士课程，由30多名秘鲁/外国博士和博士生授课，其中许多人得到了NIH研究和培训拨款的资助。我们在连续两个队列中培训了43名学生，第一个队列中的学生在培训一年内在同行评议的期刊上发表了13篇论文。已经取得了重要进展，但仍需要作出实质性努力。更新建议将通过以下方式巩固我们的工作：1)支持当前受训人员完成学位学习并帮助他们返回秘鲁，2)在秘鲁完全建立一个世界级的、可自我维持的流行病学硕士课程，3)通过夏季流行病学研究所拓宽秘鲁的培训选择，4)通过4个有标志的硕士奖学金在安第斯卫生部建设能力，5)正式增加疾病预防控制中心和圣马科斯大学作为主要合作伙伴。第二个奖项将资助2名博士生、20名硕士毕业生和21名证书项目的学生，其中30%在美国接受培训。该联盟将继续使用经过验证的、成功的方法，将课程作业、应用研究和指导成就驱动的进步相结合，并使用所有可用的培训计划。学员将准备一份方案，获得IRB的批准，进行研究，提交手稿，并申请外部资金，完成研究周期。培训将在该联盟的一流环境中进行，其中包括许多成功的NIH合作，广泛的多年研究，大量训练有素的本地和外国导师，先进的实验室，以及不同的现场和临床地点。 公共卫生相关性：我们在第一个奖项中建立了可持续的研究能力，在秘鲁创建了一个高质量的流行病学硕士项目，并与美国的高级学位培训相结合。首批受训人员正在进行关于季节性和大流行流感的重要研究，并迅速发表了重要研究。更新提案应通过在秘鲁开展进一步的地方培训来巩固这些努力，联系安第斯国家的卫生部，并在秘鲁完成建立自我可持续的高级方案。

DESCRIPTION (provided by applicant): The current influenza pandemic has made evident the gaps in knowledge about and response capacity for emerging infectious diseases. In the first stage of our award, "Peru Infectious Diseases Epidemiology Research Training Consortium", the NMRCD-UPCH-JHBSPH-USUHS consortium has contributed to building sustainable research capacity in Peru. Two Masters' graduates and one PhD candidate returned to Peru and are studying key epidemiologic and ecologic aspects of pandemic and seasonal influenza, and three trainees are finishing coursework. Also, we established a nearly self-sustainable, tuition-funded Epidemiology Masters in Peru which is taught by 30+ Peruvian/foreign PhDs and PhD candidates, many funded by NIH research and training grants. We have trained 43 students in two successive cohorts, and students from the first cohort have published 13 papers in peer-reviewed journals within a year of training. Important progress has been made, but substantial efforts are still needed. The renewal proposal will consolidate our work by 1) supporting degree completion of current trainees and nurturing return to Peru, and 2) complete establishment a world-class and self-sustainable Epidemiology Masters program in Peru, 3) broadening training options in Peru via a Summer Institute of Epidemiological Research, 4) build capacity in Andean Ministries of Health through 4 ear-marked Masters scholarships, 5) formally adding the CDC and Universidad San Marcos as key partners. This second award will support 2 PhD students, 20 Masters Graduates and 21 students of certificate programs, 30% of them trained in the US. The consortium will continue to use the proven, successful approach of combining coursework, applied research, and mentored achievement-driven progression and using all training programs available. Trainees will prepare a protocol, obtain IRB approval, conduct research, submit a manuscript, and apply for external funding, completing the research cycle. Training will take place in a superb environment of the consortium which includes numerous successful NIH collaborations, extensive multi-year research, a large pool of highly trained local and foreign mentors, sophisticated laboratories, and diverse field and clinical sites. Public Health Relevance: We built sustainable research capacity in our first award by creating a high-quality Epidemiology Masters Program in Peru and combining with advanced degree training in the US. The first trainees are conducting important studies on seasonal and pandemic influenza and published important studies rapidly. The renewal proposal should consolidate these efforts with further local training in Peru, reaching out to Ministries of Health in Andean countries and complete establishing self-sustainable advanced programs in Peru