Administrative Core

ABSTRAC-行政核心 需要协调良好的基础设施、多机构和多学科 针对特定人群的协作网络，促进高质量、经济高效和 合规研究和卫生保健战略。拉美裔临床和医疗联盟 转化性研究(联盟)将整合临床和转化性研究 跨越以西班牙裔为主的美国司法管辖区的基础设施和资源，以弥补差距 在基础和临床转化研究之间，以应对严重的健康状况 不成比例地影响医疗服务不足的人，并在西班牙裔中高度流行 人口。联盟行政核心的长期目标是提供一个模式 为了优化管理和开发临床和转化性研究基础设施 资源有限的环境，为医疗服务不足的人群提供护理。具体的 行政核心的目标将是建立一个领导和管理结构 这将确保有效和高效地实现联盟KCA和里程碑，并 必要时重新调整现有的机构和联盟资源。这将是 通过三个具体目标实现：1)提供一个综合的组织结构， 领导和咨询支持系统，以有效监督、管理和监测进展 在导致实现拟议目标的所有联盟关键组成部分活动/核心中 里程碑；2)制定和实施确保效率的政策、程序和做法； 可持续性、科学和财政灵活性，以适应不断变化的需求和优先事项 带来了新的创新和竞争的临床和翻译领域 研究；3)提供及时的财务、传播、沟通和评价职能 促进创新临床和转化性研究和服务的扩展，并长期 联盟的可持续性。拟议的行政结构将把主要领导人聚集在一起 来自参与机构和外部合作者，进一步发展了一个预先存在的 成功地获得外部资金和发展的协作结构 早期调查人员。它将提供高效和综合的治理和行政管理 这一结构将确保最佳和具有成本效益的资源利用。这最终将是 导致临床和翻译研究在我们的流行条件下取得成功进展 人口。

ABSTRAC- ADMINISTRATIVE CORE There is a need for well-coordinated infrastructure, multi-institutional and multidisciplinary collaborative networks that target specific populations and facilitate high-quality, cost-efficient and regulatory compliant research and health care strategies. The Hispanic Alliance for Clinical and Translational Research (the Alliance) will integrate clinical and translational research infrastructure and resources across a predominantly Hispanic U.S. jurisdiction to bridge the gaps between basic and clinical translational research, to address severe health conditions that disproportionately affect the medically underserved, and highly prevalent among Hispanic populations. The long-term goal of the Administrative Core of the Alliance is to provide a model for the optimal management and development clinical and translational research infrastructure in resource-limited settings that provide care to medically underserved populations. The specific objective of the Administrative Core will be to establish a leadership and management structure that will ensure that the Alliance KCA’s and milestones are met effectively and efficiently and when necessary realign the existing institutional and Alliance resources. This will be accomplished through three specific aims: 1) Provide an integrated organizational structure, leadership and advisory support system to effectively supervise, manage and monitor progress of all the Alliance key component activities/cores leading to achievement of the proposed milestones; 2) Develop and implement policies, procedures, and practices that ensure efficiency, sustainability, and scientific and fiscal flexibility to accommodate the changing needs and priorities of the Investigators, leading to new innovative and competitive areas of clinical and translational research; 3) Provide timely financial, dissemination, communication and evaluation functions that promote expansion of innovative clinical and translational research and services and long-term sustainability of the Alliance. The proposed administrative structure will bring together key leaders from the participating Institutions and external collaborators, further developing a pre-existing collaborative structure that has been successful in obtaining external funding and developing early-stage investigators. It will provide an efficient and integrated governance and administrative structure that will ensure the optimal and cost-effective utilization of resources. This will ultimately lead to successful advances in Clinical and Translational research in prevalent conditions in our population.