一种简单的仪器，用于对 16-EPA 优先多环芳烃进行原位时间分辨形态测量。-猫眼课题宝

一种简单的仪器，用于对 16-EPA 优先多环芳烃进行原位时间分辨形态测量。

批准号：

10010866

负责人：

Arantzazu Eiguren Fernandez

金额：

$18.75万

依托单位：

AEROSOL DYNAMICS, INC.

依托单位国家：

美国

项目类别：

财政年份：

2020

资助国家：

美国

项目状态：

已结题

起止时间：

2020-04-14 至 2022-03-31

来源：

https://reporter.nih.gov/project-details/10010866

关键词：

Address Air Aromatic Polycyclic Hydrocarbons Assessment tool Atherosclerosis Breathing Carcinogens Cells Chemicals Collection Complex Custom Data Databases Detection Devices Disease Environment Exposure to Feasibility Studies Gas Chromatography Gases Goals Guidelines Hazardous Substances Health Heating Human Human Resources In Situ Individual Infant International Agencies Laboratories Lead Liver Malignant Neoplasms Measurement Measures Metabolic Biotransformation Metals Methods Monitor Morphologic artifacts Motor Vehicles National Institute of Environmental Health Sciences Outcome Performance Phase Poison Publishing Recovery Research Resolution Risk Assessment Sampling Sensitivity and Specificity Specificity System Techniques Testing Time Tube United States Environmental Protection Agency World Health Organization base cigarette smoke cognitive development cost detector exhaust exposed human population genotoxicity instrument miniaturize neurodevelopment particle performance tests phase 1 study photoionization portability prenatal exposure prototype response sample collection temporal measurement ultrafine particle vapor wood smoke

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中文摘要

翻译

项目摘要人们经常接触多环芳烃（PAH）。多环芳烃在我们的环境，长期暴露可导致许多不利的健康疾病，包括认知和婴儿神经发育延迟（产前暴露）、动脉粥样硬化、肝脏问题和癌症。开发一种能够提供半连续环境PAH水平的简单仪器将填补时间变异性数据，并可提供准确信息，我们对多环芳烃在不良健康后果中的影响的理解。

英文摘要

PROJECT SUMMARY People are exposed to Polycyclic Aromatic Hydrocarbons (PAHs) regularly. PAHs are ubiquitous in our environments, and long-term exposure can lead to many adverse health diseases, including cognitive and neural development delay in infants (prenatal exposure), atherosclerosis, liver problems and cancer. Developing a simple instrument capable of providing semi-continuous levels of ambient PAH will fill the gap of temporal variability data in exposure assessment studies and could provide accurate information to increase our understanding of the effect of PAHs in adverse health outcomes.

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