Shared Resource 11: Tissue Microarray and Imaging

组织微阵列与影像共享资源 项目摘要/摘要 组织微阵列和成像共享资源(TMI)通过 新的潜在药物靶点的发现和验证。这是通过提供对此 资源，以及实现基于计算机的图像分析和高通量核酸提取。这个 CORE致力于构建、成像和分析高质量的癌症组织微阵列 研究，以及从福尔马林固定的石蜡包埋组织中高通量分离DNA和RNA。 它目前是DF/HCC社区内唯一能够建造大型- 大规模、高质量的组织微阵列。总之，组织微阵列能够大规模、高通量地 基因和蛋白质表达的原位分析。

Tissue Microarray & Imaging Shared Resource Project Summary / Abstract The Tissue Microarray and Imaging Shared Resource (TMI) facilitates translational research through the discovery and validation of novel potential drug targets. This is accomplished by providing access to this resource, as well as enabling computer-based image analysis and high-throughput nucleic acid extraction. The Core is dedicated to the construction, imaging, and analysis of high-quality tissue microarrays for cancer research, as well as high-throughput isolation of DNA and RNA from formalin-fixed, paraffin-embedded tissues. It is currently the only centralized facility within the DF/HCC community that is capable of constructing large- scale, high-quality tissue microarrays. In summary, tissue microarrays enable large-scale, high-throughput in situ analysis of gene and protein expression.