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中文摘要
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项目总结 该Roybal协调中心加速翻译老龄化研究(RCATAR)的总体目标 是提供战略领导、高效协调、鼓舞人心的支持和创造性的传播 罗伊巴尔中心的科学进步。我们将支持罗伊巴尔联盟的科学家进行 老龄行为和社会科学中的翻译研究。联盟科学家将使用NIH 行为干预发展的阶段模型作为他们选择下一个合适飞行员的指南 干预发展活动。他们的最终目标是在全球范围内推出独立研究项目 无数的老龄化和痴呆症照顾者的话题。我们将为以下方面的协调努力提供国家领导 Roybal联盟通过:1)支持他们的需求;2)为他们的积极参与创造机制;3) 让人们看到他们的科学进步;以及4)促进合作和创新。在我们的方法中,我们将 由一个指导我们所有拟议活动设计的首要原则提供信息:科学家需要 是时候思考、写作和实验了。对于任何对老龄化科学做出创造性、实质性贡献的人来说,科学家的时间是 一种关键的、经常无法表达的活性成分。增加科学家必须专注于他们的科学意志的时间 作为我们的原则,计划向罗伊巴尔中心提供的支持、促进和协调 以及他们的科学家。 RCATAR将作为年度Roybal会议、每月电话会议和其他活动的中心资源 罗伊巴尔中心联合会所需的活动。它将通过与NIA计划密切合作来做到这一点 官员和其他关键利益攸关方。具体来说,我们将利用团队科学和在线社区 协调、沟通和促进罗伊巴尔获奖者发人深省活动的方法。我们 将使用尖端信息科学原理来建立、管理和维护Roybal集中式 登记以跟踪Roybal飞行员的招募、保留、进展和发布。我们将利用我们的联合 为Roybal科学家提供系统的文献搜索、写作和文案编辑支持的专业知识。AS 在RCATAR,我们将提供多Roybal试点资金,加快最佳实践的共享,并设计 开展联动活动,打造创新伙伴关系。为了积极建立可见的科学进步,我们将 设计一个公共网站,以托管网络研讨会、试点结果、出版物、成果和相关链接。我们会 就罗伊巴尔中心的影响作为科学和公众社区的联络人。我们会 设计和监控评估系统,以确定罗伊巴尔中心的影响。最后,培育 协作我们将支持创建联合手稿、演示文稿、研讨会和视频,以及 为Roybal科学家寻找特刊和其他有声望的渠道。我们的RCATAR有 支持罗伊巴尔中心履行发展承诺所需的经验和专业知识 对老年人和照顾他们的人的生活产生广泛影响的行为干预。
英文摘要
PROJECT SUMMARY The overall goal of this Roybal Coordinating Center to Accelerate Translational Aging Research (RCATAR) is to provide strategic leadership, efficient coordination, inspired support, and creative dissemination of the scientific advances for the Roybal Centers. We will support Roybal Consortium scientists as they conduct translational research in the behavioral and social sciences of aging. Consortium scientists will use the NIH Stage Model of behavioral intervention development as their guide for selecting the next appropriate pilot intervention development activity. Their ultimate goal is to launch independent programs of research across a myriad of aging and dementia caregiver topics. We will provide national leadership for the coordinated efforts of the Roybal confederation by: 1) supporting their needs; 2) creating mechanisms for their active involvement; 3) making visible their scientific advances; and 4) fostering collaboration and innovation. In our approach, we will be informed by one overarching principle that will guide the design of all of our proposed activities: Scientists need time to think, write, and experiment. For any creative, substantive contribution to aging science, scientist’s time is a key, frequently unarticulated active ingredient. Increasing the time scientists have to focus on their science will serve as our principle on which to plan the support, facilitation, and coordination provided to the Roybal centers and their scientists. The RCATAR will serve as the central resource for the annual Roybal meetings, monthly phone calls, and other activities as needed by the Roybal Center Confederation. It will do so by working closely with the NIA Program Officer and the other key stakeholders. Specifically, we will leverage team science and online community approaches to coordinate, communicate, and facilitate thought-provoking activities for Roybal awardees. We will use cutting-edge information science principles to establish, curate, and maintain a Roybal centralized registry to track Roybal Pilot recruitment, retention, progress, and publications. We will draw upon our joint expertise to provide systematic literature search, writing, and copy-editing support to the Roybal scientists. As the RCATAR, we will provide multi-Roybal pilot funding, accelerate the sharing of best practices, and design linkage activities to forge innovative partnerships. To proactively establish visible scientific advances we will design a public website to host webinars, pilot results, publications, achievements, and relevant links. We will serve as point contacts for the scientific and public communities about the impact of Roybal Centers. We will design and monitor an evaluation system to determine the impact of the Roybal Centers. Finally, to foster collaboration we will support the creation of joint manuscripts, presentations, workshops, and videos, and seek opportunities for special issues and other prestigious outlets for Roybal scientists. Our RCATAR has the experience and expertise needed to support the Roybal centers as they fulfill their promise to develop behavioral interventions with wide impact on the lives of older adults and those who care for them.
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Optimization of monitoring, prediction and phenotyping of deterioration of inhospital patients using machine learning and multimodal real time data
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