Pulmonary Immunopathology

项目总结 肺部免疫病理学(PIP)核心为科布雷的研究人员提供专业知识和技术支持 程序。拟议的PIP核心的目标是提供动物和设备设施和专门的 对Cobre PJI进行肺免疫病理技术培训并开发新的实验 将帮助有前途的初级调查人员(PJL)和其他由NIH资助的调查人员 成功地追求他们的研究目标。这一核心的建立将促进 路易斯安那州的研究人员和生物医学研究社区的成员。这个核心还将 教育我们未被充分代表的少数民族(URM)本科生、研究生、博士后 研究员，暑期学者(DVM学生)与肺的应用和最新进展 通过讲座、实验室课程和研讨会学习免疫学。为了确保这次会议的成功 在肺部生物学和疾病以及我们的Cobre PJI方面，PIP核心的建立对于 满足路易斯安那州立大学和其他机构的当前和未来需求，因为这是该州唯一的PIP核心 路易斯安那州。因此，PIP核心计划成为路易斯安那州立大学的永久核心，我们将建立、扩展和 在15年的科布雷支持期间过渡到一个独立的核心。PIP核心已经建立了3个具体的 目标。目标1是对野生型(对照)和小鼠基因工程小鼠进行集中管理 菌落和免疫试剂。目标2是为科布雷和其他生物医学研究人员提供 关于对小鼠进行全面免疫病理评估的资源，包括仪器、技术 支持和咨询。目标3是教育教职员工、博士后研究员、研究生、 本科生和暑期学者关于申请和当前的进展 对小鼠的免疫病理评估。

PROJECT SUMMARY Pulmonary Immunopathology (PIP) core offers expertise and technical support for investigators in the COBRE program. The goal of the proposed PIP Core is to provide animal and equipment facilities and specialized training for COBRE PJIs in pulmonary immunopathological techniques and to develop new experimental approaches that will assist Promising Junior Investigators (PJls) and other NIH-funded investigators to successfully pursue their research objectives. The establishment of this core will facilitate collaboration among investigators and members of the biomedical research community in Louisiana. This core will also educate our underrepresented minority (URM) undergraduate students, graduate students, postdoctoral fellows, summer scholars (DVM Students) with the application and the current advances in pulmonary immunology through lectures, laboratory classes, and workshops. In order to ensure the success of the COBRE in Lung Biology and Disease and of our COBRE PJIs, establishment of the PIP Core is essential to meet the current and future needs of LSU and other institutions because this is the only PIP core in the state of Louisiana. Thus, the PIP Core is intended to be a permanent core at LSU that we will establish, expand, and transit to an independent core during the 15-year COBRE support. The PIP Core has established 3 specific aims. Aim 1 is to centralize management of wild-type (control) and mouse genetically engineered mouse colonies and immunological reagents. Aim 2 is to provide the COBRE and other biomedical investigators with resources on comprehensive immunopathological assessments for mice, including instrumentation, technical support and consultation. Aim 3 is to educate faculty, staff, postdoctoral fellows, graduate students, undergraduate students and summer scholars regarding the application and the current advances in immunopathological assessments for mice.