Clinical Research Laboratory

该临床实验室中心将提供一个高效的集中实验室，用于常规处理， 分析临床标本，以支持项目1和2。核心实验室的具体职能 为： 1.处理临床研究（项目1）中采集的血液和液体样本，用于 项目1和2以及本核心， 2.为项目1和2进行诊断性血清学和病毒学检测， 3.通过荧光RT-PCR定量血浆/血清样本中的登革病毒RNA水平， 项目1和2，以及 4.对项目1和2的新鲜血液样本进行流式细胞术分析。 核心实验室将设在武装部队病毒学部的设施内。 位于泰国曼谷和甘榜府的医学科学研究所。新闻部 在黄病毒学和临床研究方面拥有超过40年的经验。 核心临床实验室将在泰国运作，以处理大量临床标本 收集在本研究计划，并将执行项目1和2的常规实验室测试。这 组织为支持我们的研究提供了一个有效的常规程序系统。

This Clinical Laboratory Core will provide an efficient centralized laboratory for routine handling and analyses of clinical specimens in support of Projects 1 and 2. The specific functions of the Core Laboratory are: 1. To process blood and fluid samples collected in the clinical studies (Project 1) for utilization in Projects 1 and 2 and this Core, 2. To perform diagnostic serologic and virologic assays for Projects 1 and 2, 3. To quantify the levels of dengue virus RNA in plasma/serum samples by fluorogenic RT-PCR for Projects 1 and 2, and 4. To perform flow cytometry analyses on fresh blood samples for Projects 1 and 2. The Core Laboratory will be located in facilities of the Department of Virology, Armed Forces Research Institute of Medical Sciences in Bangkok and Kamphaeng Phet, Thailand. The Department has over 40 years of experience in flavivirology and clinical studies. A Core Clinical Laboratory will operate in Thailand to process the large number of clinical specimens collected in this research program and will perform routine laboratory tests for Projects 1 and 2. This organization provides an efficient system for routine procedures that support our research.