Sociobehavioral Sciences Research to Improve Care for HIV Infection in Tanzania

摘要： 坦桑尼亚的艾滋病毒血清阳性率估计为4.7%，140万艾滋病毒携带者 感染。它在最佳护理和预防服务方面面临重大障碍，包括缺乏 艾滋病毒相关知识、精神疾病和药物滥用的共病、贫困、农村 居住、有限的卫生保健基础设施以及卫生保健人员数量不足。 坦桑尼亚领导层和PEPFAR国家行动计划优先考虑 检测服务，优化抗逆转录病毒治疗(ART)的依从性，促进勤奋 通过病毒载量测试监测抗逆转录病毒治疗，并解决精神疾病和 滥用药物。在这方面，在以下方面发展国内研究专门知识的重要性 社会行为和执行科学是非凡的。 杜克大学全球卫生研究所(DGHI)和乞力马扎罗基督教医疗中心 (KCMC)/乞力马扎罗基督教医科大学学院(KCMU Co)合作开发 这样的专业知识。他们有一个强大的研究组合，由六个不同的NIH研究所支持。 发展研究专门知识一直是一个优先事项，并得到四个D43的支持 奖项和医学教育伙伴关系倡议。在我们目前的D43筹资周期中， 艾滋病毒和社会行为科学研究培训方案支持了 三名博士，一名医学硕士(MMED)，三名公共卫生硕士，以及 三名短期受训人员建设研究能力。这些培训中的许多都是在 开普敦大学(UCT)与KCMC/KCMU Co. 在这次竞争性续订申请中，我们建议进行培训，以进一步扩大和巩固这些 最初的努力。候选人将接受实施科学方面的博士培训(北方大学 卡罗莱纳)和心理学(UCT)、精神病学MMED(UCT)、公共卫生硕士(UCT)和短期 训练。完成后，这些科学家将加入当前D43培训周期的那些人，以 组建一支具有广泛专业知识的有才华的团队，以执行严格的社会行为和 实施科学研究。他们将一起进入有限的飞行员池 通过这项提议为他们提供研究资金，以进一步推动他们走向独立的道路。他们将收到 KCMC/KCMU学院的研究环境和文化提供了强有力的制度支持， 世界卫生组织还同意设立社会行为科学系和社会行为学系 回到莫希后，医疗队将接待科学家。

Abstract: Tanzania has an estimated HIV seroprevalence of 4.7%, and 1,400,000 persons living with HIV infection. It faces significant obstacles to optimal care and prevention services including a lack of HIV-related knowledge, co-morbidities of mental illness and substance abuse, poverty, rural residence, limited health care infrastructure, and inadequate numbers of health care personnel. Tanzanian leadership and the PEPFAR Country Operating Plan have prioritized the uptake of testing services, optimizing adherence to antiretroviral therapy (ART), promoting diligent monitoring of ART with viral load testing, and addressing co-morbidities of mental illness and substance abuse. In this context, the importance of developing in-country research expertise in sociobehavioral and implementation sciences is extraordinary. The Duke University Global Health Institute (DGHI) and Kilimanjaro Christian Medical Center (KCMC)/Kilimanjaro Christian Medical University College (KCMU Co) have partnered to develop such expertise. They have a robust portfolio of research supported by six different NIH Institutes. Development of research expertise has been a priority, and has been supported by four D43 awards and the Medical Education Partnership Initiative. In our current D43 funding cycle, the HIV and Sociobehavioral Sciences Research Training Program has supported the trainings of three PhD's, one Master's of Medicine (MMed) in Psychiatry, three Master's in Public Health, and three short-term trainees to build research capacity. Many of these trainings have occurred in a South-South relationship between the University of Cape Town (UCT) and KCMC/KCMU Co. In this competitive renewal application, we propose trainings to further expand and solidify these initial efforts. Candidates will pursue PhD trainings in implementation science (University of North Carolina) and Psychology at (UCT), MMed in Psychiatry (UCT), MPH (UCT), and short-term trainings. Upon completion, these scientists will join those from the current D43 training cycle to form a talented team with a breadth of expertise to perform rigorous sociobehavioral and implementation science research. Together they will have access to a limited pool of pilot research funds through this proposal to further their pathway to independence. They will receive strong institutional support from the research environment and culture of KCMC/KCMU College, who have also agreed to create Departments of Sociobehavioral Sciences and Sociobehavioral Medicine to host the scientists upon return to Moshi.