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中文摘要
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项目总结 纽约大学癌症健康差距(CHD)孢子发育研究计划(DRP)的总体目标 是鼓励新的翻译研究,以减少少数族裔和 低收入人群。纽约大学CHD孢子DRP的目标是:1)为有前途的研究提供资金 口腔消化系癌症的健康差异与微生物群和免疫的相互作用有关 回应;2)寻求支持开展“高风险、高回报”的ODT癌症调查;3)吸引 研究人员提出了新的方法来解决导致口腔消化系癌症健康差异的问题 癌症;以及4)监测发展研究项目的进展。这项计划将促进 通过资助拟议的试点项目探索翻译ODT癌症差异研究的创新思路 由助理教授级别或更高级别的调查人员。DRP将提供指导、建议、评估、 以及为5-7个试点项目提供资金。具体地说,DRP每年将支持至少2个试点项目,每个试点项目 12个月,可选择再竞争续签12个月。每个试点项目的目标 是生成足够的高质量数据来推进对ODT癌症的研究,以使其能够 向美国国立卫生研究院或其他联邦机构提交令人信服的独立项目以获得资金。我们将鼓励 DRP项目,链接到正在进行的纽约大学CHD孢子项目。DRP的联席主任是乔治博士 米勒和周亭-谢弗林博士。米勒博士是外科和细胞生物学教授,也是Perlmutter的领导人 综合癌症中心(PCC)肿瘤免疫学项目。周亭-谢弗林博士是助理医生 人口健康教授兼公共政策委员会负责社区推广和参与的副主任。
英文摘要
PROJECT SUMMARY The overall goal of the NYU Cancer Health Disparity (CHD) SPORE Developmental Research Program (DRP) is to stimulate novel translational research to reduce orodigestive (ODT) cancer disparities among minority and low-income populations. The aims of the NYU CHD SPORE DRP are to: 1) provide funds for promising research in cancer health disparities in orodigestive cancers as it relates to the interplay of the microbiome and immune response; 2) seek to support the development of “high-risk, high-reward” investigations in ODT cancers; 3) attract investigators with novel approaches to solving issues that contribute to cancer health disparity in orodigestive cancers; and 4) monitor the progress of developmental research projects. This program will promote the exploration of innovative ideas in translational ODT cancer disparities research by funding pilot projects proposed by investigators at the Assistant Professor level or higher. The DRP will provide guidance, advice, evaluation, and funding for 5–7 pilot projects. Specifically, the DRP will support at least 2 pilot projects per year, each for a 12-month period, with the option of a competitive renewal for another 12 months. The goal for each pilot project is to generate sufficient high-quality data to advance investigation of ODT cancers to the extent that it will enable submission of a compelling independent project to the NIH or other federal agency for funding. We will encourage DRP projects that link to an ongoing NYU CHD SPORE project. The co-Directors of the DRP are Dr. George Miller and Dr. Chau Trinh-Shevrin. Dr. Miller is Professor of Surgery and Cell Biology and leader of the Perlmutter Comprehensive Cancer Center (PCC) Tumor Immunology Program. Dr. Chau Trinh-Shevrin is Associate Professor of Population Health and Associate Director for Community Outreach and Engagement in the PCC.
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