Core I: Biostatistics Core

项目摘要/摘要 生物统计共享资源核心(BSRC)在加强U54研究方面发挥了关键作用 基础设施。BSRC由具有专业知识和经验的生物统计学家领导 在太平洋岛屿人口中，癌症研究取得了显著的成功。BSRC增加了科学的严谨性 通过健全的统计咨询和纳入新的方法，如答复者，对U54研究进行评估 当前项目中的驱动抽样和中期分析方案。BSRC为所有 研究工作的量化方面，包括研究设计、数据管理、统计 编程、数据分析以及结果的解释和展示。一名首席生物统计师被指派 向每个U54研究项目提供咨询，以便在整个研究期间提供咨询。BSRC的领导人为 作为U54内部咨询委员会的无投票权成员，并提供对以下方面的统计审查和投入： 新的研究理念。共享资源建设了加州大学健康差异研究的能力 关岛和夏威夷大学癌症中心通过对教职员工和学生进行量化指导 方法，从而建设研究能力，并通过正式研讨会。此外，BSRC将促进 通过收集关于癌症风险和癌症风险及保护因素流行情况的信息进行研究 关岛和夏威夷将用于为研究项目提供信息，并通过创建和提供信息 技术共享资源，存储和共享当前和过去的U54项目数据的平台，以及 文件。

PROJECT SUMMARY/ABSTRACT The Biostatistics Shared Resource Core (BSRC) serves a critical role in enhancing the U54 research infrastructure. The BSRC is led by biostatisticians who have the expertise and experience to contribute substantially to successful cancer research in Pacific Island populations. The BSRC adds to the scientific rigor of U54 research through sound statistical advice and inclusion of novel approaches, such as Respondent Driven Sampling and an interim analysis scheme in current projects. The BSRC provides support for all quantitative aspects of research endeavors, including study design, data management, statistical programming, data analysis, and interpretation and presentation of results. A primary biostatistician is assigned to each U54 research project in order to provide consultation throughout the study. The BSRC Leaders serve as non-voting members of the U54 Internal Advisory Committee and provide statistical review of, and input to, new research concepts. The Shared Resource builds capacity for health disparities research at University of Guam and the University of Hawai`i Cancer Center through mentoring of faculty and students on quantitative methods, thus building research capacity, and through formal seminars. Additionally, the BSRC will facilitate research through curation of information on cancer risks and prevalence of cancer risk and protective factors in Guam and Hawai`i to be used to inform research projects and through creation, with the Information Technology Shared Resource, of a platform for storage and sharing of current and past U54 project data and documents.