Understanding how Powered Componentry Impacts K2-Level Transfemoral Amputee Gait

项目摘要 电动假体膝关节和踝关节可以主动产生扭矩，潜在地实现安全和高效 执行要求更高的移动任务，如爬坡道和楼梯或坐到站 转型和提高能源效率。然而，可用的动力元件已经几乎 专为在联邦医疗保险功能分类级别行走的个人开发和测试 (MFCL)K3-或K4。被指定为K2级救护车的个人(即，行走更有限 能力)通常是一种被动假体，但这些人已被证明受益于 更先进的微处理器控制的膝盖，并可能获得额外的好处，从动力组件。 由于现有的动力部件很重，我们开发了轻便、全动力的膝盖和脚踝 适用于K2级救护车的部件，可以单独使用，也可以一起使用。这些 设备将使我们能够评估与在膝盖、脚踝或膝盖提供动力相关的好处，以及 脚踝，以及与一个或多个动力装置的额外重量和控制复杂性相关的权衡 组件。我们的目标是确定动力假体部件如何影响功能-就以下方面而言 单侧股骨头K2水平步行者的代谢成本、步态生物力学和功能活动能力 截肢，使用规定的被动假体。我们将招募20名个人，他们将参与 三个目标，预计15个将完成研究。对于目标1，受试者将首先配备完整的 被动设备(Ottoock C-Leg 4 MPK和Triton 1C60 Foot)，然后是我们的全动力设备(膝盖+ 脚踝假体)。在完成截肢者移动性预测之前，他们将接受使用每种设备的培训 通过假体(AMPPRO)(主要结果)以及代谢和生物力学评估，一套 标准结果衡量标准和自我报告调查(次要结果)。对于目标2，我们将评估 动力膝关节+被动踝关节和被动膝盖+动力踝关节的组合，按随机顺序进行。科目 将接受使用每种设备的培训，并将执行相同的主要和次要结果衡量标准 评估膝关节或脚踝的额外重量对功能的益处和影响。在目标3中，我们将提供 强化训练，使受试者能够独立执行典型的日常生活活动，并实现 使用动力膝盖+脚踝设备的个人移动性目标，以确定K2- 救护车可以达到的水平。受试者将再次完成相同的主要和次要结果测量 使用供电设备，并使用目标1中的被动设备重复这些措施 适应以前目标的培训效果的结转。预期的结果是对 假肢部件的功率和重量如何影响K2级步行器的功能，这将使 最佳选择组件以改善被指定为受限个体的功能活动能力 社区救护车，目前仅限于被动设备。

Project Summary Powered prosthetic knee and ankle joints can actively generate torque, potentially enabling safe and efficient performance of more demanding mobility tasks, such as ascending ramps and stairs or performing sit-to-stand transitions, and improving energy efficiency. However, available powered components have been almost exclusively developed for and tested by individuals ambulating at Medicare Functional Classification Level (MFCL) K3-or K4. Individuals designated as K2-level ambulators (i.e., have a more limited ambulation capacity) are typically prescribed a passive prosthesis, but these individuals have been shown to benefit from more advanced microprocessor-controlled knees and may gain additional benefit from powered components. Because available powered components are heavy, we developed lightweight, fully powered knee and ankle components that can be used separately or together and are appropriate for K2-level ambulators. These devices will allow us to evaluate the benefits associated with providing power at the knee, ankle, or knee and ankle, and the tradeoffs associated with the additional weight and control complexity of one or more powered components. Our goal is to determine how powered prosthetic components effect function—in terms of metabolic cost, gait biomechanics, and functional mobility in K2-level ambulators with a unilateral transfemoral amputation, who use a prescribed passive prosthesis. We will recruit 20 individuals, who will participate in three aims, with the expectation that 15 will complete the study. For Aim 1, subjects will be fit first with a fully passive device (Ottobock C-Leg 4 MPK and a Triton 1C60 Foot) and then to our fully powered device (knee-+ ankle prosthesis). They will be trained to use each device before completing the Amputee Mobility Predictor with Prosthesis (AMPPRO) (primary outcome) as well as metabolic and biomechanical assessments, a set of standard outcome measures, and self-report surveys (secondary outcomes). For Aim 2, we will evaluate combinations of powered knee + passive ankle and passive knee + powered ankle, in random order. Subjects will be trained to use each device, and the same primary and secondary outcome measures will be performed to assess functional benefits and the effects of additional weight at the knee or ankle. In Aim 3, we will provide intensive training to enable subjects to independently perform typical activities of daily living and achieve personal mobility goals using the powered knee + ankle device, to determine what level of improvement K2- level ambulators can attain. Subjects will again complete the same primary and secondary outcome measures using the powered device and will repeat these measures using the passive device from Aim 1, to accommodate carryover of training effects from previous Aims. The anticipated outcome is an understanding of how power and the weight of prosthetic components affect function in K2-level ambulators, which will enable optimal selection of components to improve functional mobility in individuals who are designated as limited community ambulators and currently restricted to passive devices.