Administrative Core

抽象管理核心 行政核心将支持我们的IPCAVD的科学和计划活动 计划并为计划提供必要的基础设施，以实现其总体目标 以最高效和最有效的方式实现研究目标和里程碑。这个核心有 具体目标如下：（1）科学领导和协调IPCAVD的 活动，确保实现我们的科学目标，同时最大限度地提高科学合作; (2)优化参与的科学和临床研究者之间的沟通; 项目负责人、外部科学顾问委员会、NIAID和我们的临床 （3）提供财政监督、行政支持，并确保监管和 授予策略遵从性。它将由主要研究者Leonidas Stamatatos博士领导， 谁将管理，监督和协调每个参与者在该计划的努力，与 项目经理沈铭超博士的协助。一组外部科学顾问 将成立一个委员会，负责监督IPCAVD的科学活动，并提供建议和支持。 该核心将监督和整合研究计划、产品开发 计划和临床开发计划。该核心负责监督本计划的所有方面，包括 科学问题、管理事务、财务、沟通、协调和行政管理 每个核心和项目。该核心将确保支出和预测 与整个项目的目标相一致;监控财务和功能方面， 所有分包合同;并在参与时与赞助研究办公室协调 补助金发放、支出和会计机构。这一核心将 协调科学和财务报告的编写和提交， 制定监管协议并确保遵守监管规定。通信将 利用各种工具，包括专用的外部IPCAVD SharePoint网站， 它将作为计划数据、法规遵从性文档 机构间和物资转让协定以及相关出版物、摘要和 介绍。

ABSTRACT ADMINISTRATION CORE The Administrative Core will support the scientific and programmatic activities of our IPCAVD Program and provide the necessary infrastructure for the Program to achieve its overall research objectives and milestones in the most efficient and effective manner. This Core has the following specific aims: (1) to provide scientific leadership and coordination of the IPCAVD’s activities, assuring achievement of our scientific goals while maximizing scientific collaboration; (2) to optimize communication among the participating Scientific and Clinical investigators; between Project Leaders, the external Scientific Advisory Board, the NIAID and our Clinical Partners; and (3) to provide fiscal oversight, administrative support, and ensure regulatory and grant policy compliance. It will be led by the Principal Investigator, Dr. Leonidas Stamatatos, who will manage, oversee and coordinate the efforts of each participant in the Program, with the assistance of the Project Manager, Dr. Mingchao Shen. A group of external Scientific Advisors will be formed to oversee the scientific activities of the IPCAVD and provide advice and support. This Core will oversee and integrate the execution of the Research Plans, Product Development Plan, and Clinical Development Plan. This Core oversees all aspects of this Program including scientific issues, regulatory affairs, finance, communication, coordination and administration of each of the Cores and Projects. This Core will ensure that expenditures and projections are commensurate with the goals of the overall project; monitor the fiscal and functional aspects of all subcontracts; and coordinate with the Offices of Sponsored Research at participating Institutions for the disbursement, expenditure and accounting of grant funds. This Core will coordinate the preparation and submission of scientific and financial reports, facilitate the establishment of regulatory protocols and ensure regulatory compliance. Communications will be facilitated utilizing a variety of tools, including a dedicated, external IPCAVD SharePoint site, which will serve as a centralized repository for Program data, regulatory compliance documents, inter-institutional and material transfer agreements and relevant publications, abstracts and presentations.