Administrative Core

行政核心在CORT的整体成功中发挥着关键作用。的主要目标 行政核心是培养一个促进CORT总体目标的科学环境： 推进对系统性硬化症（SSc）发病机制的理解，并发现新的治疗方法， SSc患者Robert Lafyatis博士将领导CORT并主持执行委员会， 每个项目和核心的主要研究者。Lafyatis医生有广泛的行政管理 领导项目，研究部门和国际会议的经验。他也有临床和 CORT研究人员将研究的所有科学领域的科学经验。拉马·马兰帕利医生 CORT副主任，哈里森法伯博士，波士顿大学网站主任和迈克尔惠特菲尔德博士， 达特茅斯医学中心主任将协助Lafyatis博士领导CORT。Mallampalli博士 在肺部疾病的转化研究和广泛的行政管理方面拥有丰富的经验 包括领导全国最大的肺科之一的经验。法伯博士以 国际上对SSc相关肺动脉高压的研究，Whitfield博士在 生物信息学和系统生物学。行政核心将组织每月的执行委员会 会议将作为一个时间来讨论任何行政问题，但更重要的是作为一个时间， 研究人员之间的科学交流。它将组建一个经验丰富的咨询委员会 由医生科学家组成，在SSc皮肤病，间质性肺病，肺 动脉高血压、生物标志物和临床结局。行政核心委员会将组织 咨询委员会的年度审查，以批评进展，探索障碍，并为新的 科学指导。CORT行政核心将管理预算，协助主任准备 报告，管理网站，监督培训，安排培训班。行政核心 将提供八个基本功能：1）为单个项目和核心提供领导，并鼓励 项目和核心之间的合作与协作; 2）提供日常的科学监督， 通过与项目和核心调查人员保持沟通，将项目作为一个整体; 3）确保 匹兹堡大学与波士顿大学之间的沟通和协调， 达特茅斯研究中心研究员; 4）为项目提供外部监督和审查机制 5）为项目提供行政支持，包括人事、财务和其他 评估试点项目和可行性项目的科学价值和方案价值 并提出建议，提交给NIAMS; 7）提供丰富的机会， 8.组织对年轻调查人员的辅导。通过这些活动，行政 核心将为所有CORT职能提供关键支持和协调。

The Administrative Core plays a key role in the overall success of this CORT. The main goal of the Administrative Core is to foster a scientific environment that promotes the overall CORT objectives: to advance the understanding of systemic sclerosis (SSc) pathogenesis and to discover novel therapies for patients with SSc. Dr. Robert Lafyatis will lead the CORT and chair the Executive Committee, composed of the principal investigators of each of the projects and cores. Dr. Lafyatis has extensive administrative experience in leading program projects, study sections, and international meetings. He also has clinical and scientific experience in all of the scientific areas to be studied by CORT investigators. Dr. Rama Mallampalli, CORT Associate Director, Dr. Harrison Farber, Boston University Site Director and Dr. Michael Whitfield, Dartmouth Medical Center Site Director will assist Drs. Lafyatis in leading the CORT. Dr. Mallampalli has extensive experience in translational investigation into pulmonary disease and broad administrative experience that includes leading one of the largest pulmonary sections in the country. Dr. Farber is known internationally for his work on pulmonary arterial hypertension associated with SSc, and Dr. Whitfield in bioinformatics and systems biology. The administrative core will organize monthly Executive Committee meetings that will serve both as a time to discuss any administrative problems, but more importantly as a time for scientific exchange between investigators. It will assemble a highly-experienced Advisory Committee composed of physician-scientists, working in the fields of SSc skin disease, interstitial lung disease, pulmonary arterial hypertension, biomarkers and clinical outcomes. The Administrative Core committee will organize annual review by the Advisory Committee to critique progress, probe obstacles, and provide advice for new scientific directions. The CORT Administrative Core will manage budgets, assist the director in preparing reports, manage the website, supervise trainess, and arrange enrichment seminars. The Administrative Core will serve eight basic functions: 1) Provide leadership for individual project and cores, and encourage cooperation and collaboration between projects and cores; 2) Provide day-to-day scientific oversight of the program as a whole by maintaining communication with and among project and core investigators; 3) Ensure communication and coordination between the University of Pittsburgh with Boston University and the Dartmouth Site Investigators; 4) Provide mechanisms for external oversight and review for the program project; 5) Provide administrative support for the program including personnel, financial and other management functions; 6) Assess the scientific merit and programmatic value of Pilot and Feasibility Projects and make recommendations for submission to the NIAMS; 7) Provide enrichment opportunities for investigators, and 8) Organize mentoring for young investigators. Through these activities the Administrative Core will provide key support and coordination for all CORT functions.