Center for Appalachian Research in Environmental Sciences-Pilot Project Program (PPP)

项目摘要--试点项目计划 肯塔基大学阿巴拉契亚研究和环境科学中心(UK-CARE)试点 项目计划(PPP)旨在支持高度创新和协作的研究，这将增强 识别和利用中心的科学主题并建立社区学术的能力 翻译领域的合作伙伴关系。这一目标将通过提供试点资金来实现 为创新的、时间敏感的初步研究和社区项目提供指导和支持 提高我们对环境暴露、人类生物学和疾病的理解。具体地说， 公私合作伙伴关系将1)支持创新、合作的环境健康研究的新机会；2) 加强互动并扩大具有多方面专业知识和经验的调查人员的临界群体 英国和阿巴拉契亚社区的学科、翻译环境健康研究；3)提供 指导和支持，以确保英国CARE试点项目的成功；以及4)评估利用情况， PPP的效率、质量和影响。英国对PPP的强有力的机构支持是我们 求婚。事实上，英国实体将提供配套资金，占为试点分配的资金总额的37% 项目。公私合作伙伴关系将提供三大类试点研究资助机会，与 英国CARE的科学主题和战略愿景。首先，试点赠款将产生新的初步数据 并支持(A)现有中心成员催生与中心一致的新研究机会 科学主题；(B)非成员科学家扩大合作，为中心带来新的方面； 以及(C)创造性的早期研究人员，以建立具有竞争力的研究计划。第二，社区 助学金将与英国教师合作者一起为社区组织提供直接支持，以解决优先事项 科学主题。第三，迷你赠款将促进快速、对时间敏感的开发，或获得新的和新颖的 技术以及社区参与的研究。PPP将沟通、协作、协调 并在中心核心和项目之间创造协同效应，以确保由试点资助的调查人员获得 他们需要援助来制定和开展他们的试点项目。PPP将与调查人员和 社区利益相关者，包括英国CARE内部和中心外的，作为审查者和受赠者 解决与暴露的环境途径(例如，水、空气)、人类生物学和新的 污染物和新出现的威胁。购买力平价的总体进展以及它如何有效地推动 环境健康研究，将通过现有的跟踪和评价部分进行监测 英国临床和转化科学中心，与行政核心协调。合并 试点资助的教师进入中心将对扩大我们中心的审查能力产生重大影响 与新出现的环境健康问题和新技术有关的重要问题，并支持 培养下一代环境健康科学家。

PROJECT SUMMARY – Pilot Project Program The University of Kentucky Center for Appalachian Research and Environmental Science (UK-CARES) Pilot Project Program (PPP) aims to support highly innovative and collaborative research studies that will enhance the ability to identify and capitalize on the Center’s science themes and build community-academic partnerships across the translational spectrum. This goal will be accomplished by providing pilot funds along with guidance and support for innovative, time-sensitive preliminary studies and community projects that improve our understanding of environmental exposures, human biology, and disease. Specifically, the aims of the PPP are to 1) support new opportunities for innovative, collaborative environmental health research; 2) enhance interactions and expand the critical mass of investigators with expertise and experience in multi- disciplinary, translational environmental health research at UK and in Appalachian communities; 3) provide guidance and support to ensure the success of UK-CARES Pilot Projects; and 4) evaluate utilization, efficiency, quality, and impact of the PPP. Strong institutional support of the PPP from UK is a hallmark of our proposal. In fact, UK entities will provide matching funds, representing 37% of the total funds allocated for pilot projects. The PPP will provide three general categories of pilot research funding opportunities consistent with the science themes and strategic vision of UK-CARES. First, Pilot grants will generate new preliminary data and support (a) established Center members to catalyze new research opportunities consistent with Center science themes; (b) non-member scientists to expand collaborations and bring new dimensions to the Center; and (c) creative, early-stage investigators to establish competitive research programs. Second, Community grants will provide direct support to community organizations with a UK faculty collaborator to address a priority science theme. Third, Mini grants will foster rapid, time-sensitive development of, or access to, new and novel technologies as well as community-engaged research. The PPP will communicate, collaborate, coordinate, and create synergy across Center cores and programs to ensure that pilot-funded investigators receive the assistance they need to develop and carry out their pilot projects. The PPP will engage investigators and community stakeholders, both within UK-CARES and outside the Center, as reviewers and grantees to address questions related to environmental pathways (e.g., water, air) to exposures, human biology, and new contaminants and emerging threats. The overall progress of the PPP, and how effectively it has promoted environmental health research, will be monitored through the existing tracking and evaluation component of UK’s Center for Clinical and Translational Science, in coordination with the Administrative Core. Incorporating pilot-funded faculty into the Center will have a major impact on expanding the ability of our Center to examine important questions related to emerging environmental health issues and novel technologies, and to bolster the development of the next generation of environmental health scientists.