Center for Environmental Health and Justice in Northern Manhattan

总结-总体组成部分 我们的世界正在迅速变化。社会、地球和技术的变化需要不断发展的愿景 解决新出现的和持续存在的环境健康挑战，从污染的空气和水到气候 变化、微塑料和新型化学品。我们也日益认识到， 低收入社区比其他社区面临更多的环境危害。所以我们的 主题是“在不断变化的世界中重新构想环境健康和正义”， 北方曼哈顿环境健康与正义中心（CEHJNM）的资助期。的 中心的工作将在反映我们的优势和利益的五个方向上进行阐述，我们将 通过相应的工作组推进：（1）环境正义;（2）推进开放体;（3） 环境数据科学;（4）生物和分子机制;（5）气候和健康 CEHJNM的使命是了解环境暴露引起的健康问题， 通过转化科学和伙伴关系解决环境不平等问题。CEHJNM位于 华盛顿高地的一个低收入社区，周围是哈莱姆和南布朗克斯的社区 受到有害环境条件的严重影响。我们的社区参与核心建立在 与我们的主要当地合作伙伴WE ACT for Environmental Justice建立了长期有效的合作关系- 一个非常引人注目的非营利哈莱姆组织，致力于环境正义，并提出了新的方法 识别和与社区团体合作，并支持研究，以检查和改善 环境卫生差距。我们的职业发展计划成功地支持了 科学家在哥伦比亚大学，现在还将与环境正义， 国家计划，培训和授权来自历史上被排斥背景的新兴调查人员。我们 综合健康科学设施核心将整合六个实验室在采样、处理、 以及最先进的环境和生物基质分析。研究设计和数据科学 Facility Core便于使用当代研究设计和广泛的数据管理， 生物统计学和数据科学方法。 CEHJNM的试点项目计划有一个6周的周转从提交到资助的完整申请 （≤ 35 K）和一周的周转时间（≤ 10 K）。试点激发了创新方向--从 从新的实验室方法到数据科学和社区合作伙伴关系， 外部资金;在本周期，87%的试点资金授予了首席研究员，他们 早期职业教师或非成员在获奖时。基于CEHJNM的成功记录，我们 通过此应用程序提出更新的组织结构、增强的服务和战略未来 我们的目标是继续应对我们时代最紧迫的地方和全球公共卫生挑战。

SUMMARY – OVERALL COMPONENT Our world is changing rapidly. Societal, planetary, and technological changes require an ever-evolving vision for solving emerging and persisting environmental health challenges, from polluted air and water to climate change, microplastics, and new types of chemicals. We have also become increasingly aware that minoritized and low-income communities confront more environmental harm than other communities. Therefore, our theme, “Re-envisioning environmental health and justice in a changing world,” captures the vision for the next funding period of the Center for Environmental Health and Justice in Northern Manhattan (CEHJNM). The Center’s work will be articulated across five directions that reflect our strengths and interests, which we will advance through corresponding working groups: (1) Environmental Justice; (2) Advancing the Exposome; (3) Environmental Data Science; (4) Biological and Molecular Mechanisms; and (5) Climate and Health The mission of the CEHJNM is to understand health concerns caused by environmental exposures and address environmental inequities through translational science and partnerships. CEHJNM is housed in the low-income neighborhood of Washington Heights, surrounded by communities in Harlem and the South Bronx disproportionally burdened by harmful environmental conditions. Our Community Engagement Core builds on a longstanding and impactful collaboration with our primary local partner, WE ACT for Environmental Justice— a highly visible non-profit Harlem organization dedicated to environmental justice and proposes new methods of identifying and collaborating with community groups and supporting research to examine and ameliorate environmental health disparities. We house a Career Development Program that has successfully supported scientists at Columbia University and will now also work with Agents of Change in Environmental Justice, a national program that trains and empowers emerging investigators from historically excluded backgrounds. Our Integrated Health Sciences Facility Core will integrate the expertise of six laboratories in sampling, processing, and state-of-the-art analysis of environmental and biological matrices. Our Study Design and Data Science Facility Core facilitates the use of contemporary study designs and a wide array of data management, biostatistics, and data science approaches. CEHJNM’s Pilot Project Program has a 6-week turnaround from submission to funding for full applications (≤35K) and one-week turnaround for mini-pilots (≤10K). Pilots have stimulated innovative directions—ranging from new laboratory methods to data science and community partnerships—and has yielded 40-fold returns in external funding; in the current cycle, 87% of the pilot funding was awarded to Principal Investigators who were early-career faculty or non-members at the time of the award. Building on CEHJNM’s record of success, we propose through this application a renewed organizational structure, enhanced services, and strategic future directions to continue to respond to the most urgent local and global public health challenges of our times.