Ultra-stable, phase sensitive, snapshot OCT system enabled by 2-Photon additive manufacturing

在本方案中，我们的目标是利用OCT的原理建立一个体积OCT快照成像的平台技术 图像映射光谱学。我们将免费演示全场谱域OCT((FFSDOCT))系统 太空。体积功能OCT将通过利用先进的双光子聚合3-D来实现 打印方法，这将允许打印任意光学质量结构。为了实现这些目标，我们 将利用Nanoscribe最先进的Quantum X系统。该设备允许将小型和 中等大小的细节，允许特征尺寸降至140 nm。印刷过程中获得的粗糙度为 在20 nm以下。印花将在透明树脂(IV-Dip、SU8类似物等)中进行。它还允许史无前例的 打印量与其他2PP打印机相比。 具体地说，概念验证全场谱域OCT将使用定制设计的3-D打印 多面镜成像并分散到2-D scmos传感器上。映射镜将合并 10,000个微型面和100个独特的倾斜，将100x100个图像点映射到相机传感器上。因此， 系统将作为并行、高分辨率光谱仪阵列运行，其中光谱仪的数量 等于对象点的数量。由此产生的FFSDOCT系统将没有活动部件，但能够 以传感器的帧速率(30赫兹)采集体积OCT图像。成像光谱仪将呈线性 样品以波数表示。 为了对系统进行评估，我们将在自由空间进行一系列成像实验。FFSDOCT将被描述为 对于分辨率、系统灵敏度、流量测量和纳米级振动。

In this proposal we aim to build a platform technology for volumetric OCT snapshot imaging using principle of Image Mapping Spectroscopy. We will demonstrate Full Field Spectral Domain OCT ((FFSDOCT)) system in free space. The volumetric functional OCT will be enabled by leveraging advanced 2Photon Polymerization 3-D printing approaches, that will permit printing of arbitrary optical quality structures. To achieve these goals, we will utilize state of the art Quantum X system from Nanoscribe. The device allows the combination of small, and medium size detail allowing feature sizes down to 140 nm. The roughness obtained in the printing process is below 20 nm. Prints will be performed in clear resins (IV-Dip, SU8 analogs etc.). It also permits unprecedented print volumes in comparison to other 2PP printers. Specifically, the proof of concept Full Field Spectral Domain OCT will use custom designed 3-D printed multifaceted mirror imaged and dispersed onto a 2-D sCMOS sensor. The mapping mirror will incorporate 10,000 miniature facets and 100 unique tilts to map 100x100 image points onto a camera sensor. In result the system will operate as an array of parallel, high resolution spectrometers where the number of spectrometers equals the number of object points. The resulting FFSDOCT system will have no moving parts yet be capable of acquiring volumetric OCT images at the frame rate of the sensor (30 Hz). The imaging spectrometer will linearly sample in wavenumber. To evaluate system, we will perform series of imaging experiments in free space. FFSDOCT will be characterized for resolution, system sensitivity, the measurement of flow and nanoscale vibrations.