Multi-Component Behavioral Activation, Nutrition, and Activity Intervention for Persons Aging with HIV

总结 这份行政补充材料将测试一份简短的（12周）个性化的， 行为激活计划的重点是减少孤独和增加社会参与，这将 通过增加家庭锻炼和解决老年人营养不良问题的方案予以加强， 艾滋病。它将由远程教练提供。招募将包括来自UM的50岁以上艾滋病毒感染者 必要时，在巴尔的摩的“繁荣”计划和其他艾滋病毒中心。这项工作将在三年内完成 第一阶段：我们会从社区参与策略开始，例如与 与艾滋病毒诊断和临床提供者，以调整干预。一个社区参与小组将 提供关于递送模式（电话、平板电脑、家庭和/或在社区中心）的偏好的反馈， 招聘战略和手册、措施、其他学习材料、纳入体育活动， 营养模块。第二阶段：我们将与艾滋病毒临床和研究专家在运动，营养， 心理功能，为远程教练定制材料和资源的内容，以便 满足PAWH的需求。第三阶段：社区参与后， PAWH，我们将对10名年龄在50岁以上的艾滋病毒诊断患者进行可行性试验。这 一项研究将测试一种急需的干预措施的可行性，以改善患者的功能和健康状况。 老年人中的弱势群体。这是一项单组非盲可行性研究，旨在探索一种新的干预措施 to support支持older老people aging老化with HIV艾滋病毒.如果这种干预似乎是可行的，可接受的，并显示 如果有初步的疗效证据，我们将在III期疗效试验中对其进行评估。它属于 UM-OAIC，旨在研究功能障碍的机制 与老年人中流行的慢性病相关;设计新颖，有效的康复 干预措施;并将干预措施转化为诊所外的实施和严格评估（例如， 家庭、老年中心、健身房）。

Summary This administrative supplement will test the feasibility and acceptability of a brief (12 week) individualized, Behavioral Activation program focused on decreasing loneliness and increasing social engagement, that will be augmented with a program to increase home exercise and address poor nutrition among persons aging with HIV. It will be delivered by remote coaches. Recruitment will include those ages 50+ with HIV from the UM THRIVE program and other HIV centers in Baltimore as necessary. This work will be accomplished in three stages: Stage 1: We will start with community engagement strategies, such as focus groups with persons aging with a HIV diagnosis and clinical providers, to tailor the intervention. A community engagement team will provide feedback on preferences for delivery mode (telephone, tablet, home, and/or at a community center), recruitment strategies and brochures, measures, other study materials, inclusion of the physical activity and nutrition modules. Stage 2: We will work with HIV clinical and research experts in exercise, nutrition, and psychological functioning to tailor the content of the material and resources for the remote coaches in order to meet the needs of PAWH. Stage 3: Following the community engagement and tailoring the intervention for PAWH, we will pilot test feasibility acceptability with 10 persons ages 50+ living with a HIV diagnosis. This study will test the feasibility of a much-needed intervention to improve functioning and health outcomes among a vulnerable group of older adults. It is a single-group unblinded feasibility study to explore a new intervention to support older people aging with HIV. If this intervention appears to be feasible, acceptable, and to show preliminary evidence of efficacy, we will look be to evaluate it in a phase III efficacy trial. It fits into the scope of the UM-OAIC, which aims to conduct research on the mechanisms that underly the functional impairments associated with prevalent chronic diseases in older people; design novel, efficacious rehabilitation interventions; and translate interventions for implementation and rigorous evaluation outside the clinic (e.g., home, senior center, gym).