The UC DPP Study: Evaluating a Diabetes Prevention Initiative Across the University of California System

项目总结/摘要 为了解决所有加州大学（UC）校园的肥胖和2型糖尿病预防问题， UC范围内的糖尿病预防倡议（简称UC DPP倡议）于2018年启动。中 研究人员和大学之间的创新科学伙伴关系，总统的UC办公室将 为UC受益人提供电子健康记录（EHR）和保险索赔，以及 加州大学五个校区的校园级数据进行严格的评估。我们将使用一个完善的 覆盖、有效性、采用、实施和维护（RE-AIM）评估框架，以确保 综合评价为了评估UC DPP倡议的有效性，我们将研究平均 12个月（主要结局）和24个月时超重/肥胖内和之间的体重变化百分比 UC受益人有患2型糖尿病的风险。为了评估覆盖范围，我们将报告符合条件的UC比例 参与DPP的受益人（参加>9和>16届）及其在UC中的代表性 整体受益人。为了研究采用、实施和维护情况，我们将进行实地考察， 定性访谈，侧重于评估执行程度，确定障碍和促进因素 与实施有关，以及意想不到的后果。总之，这是一个独特的机会， 使用UC系统中的各种数据源进行必要的评估。从这个研究结果 将为未来的加州大学范围内针对肥胖和2型糖尿病预防的项目提供信息， 其他大型大学系统和雇主的有效战略。

PROJECT SUMMARY/ABSTRACT To address obesity and type 2 diabetes prevention across all University of California (UC) campuses, a new UC-wide Diabetes Prevention Initiative (referred to as the UC DPP Initiative) was launched in 2018. In an innovative scientific partnership between researchers and the university, the UC Office of the President will provide access to electronic health record (EHR) and insurance claims for UC beneficiaries, as well as campus-level data across five UC campuses to conduct a rigorous evaluation. We will use a well-established reach, effectiveness, adoption, implementation, and maintenance (RE-AIM) evaluation framework to ensure a comprehensive evaluation. To assess the effectiveness of the UC DPP Initiative, we will examine mean percent weight change at 12-months (primary outcome) and 24-months within and between overweight/obese UC beneficiaries at risk for type 2 diabetes. To assess reach, we will report the proportion of eligible UC beneficiaries who engage in DPP (attend >9 and >16 sessions) and their representativeness of UC beneficiaries overall. To examine adoption, implementation and maintenance, we will conduct site visits and qualitative interviews, focused on assessing the degree of implementation, identifying barriers and facilitators associated with implementation, and unanticipated consequences. In summary, this is a unique opportunity to conduct an imperative evaluation using diverse data sources across the UC system. Findings from this study will inform future UC-wide programs targeting obesity and type 2 diabetes prevention, as well as dissemination of effective strategies to other large university systems and employers.