NU-TRIHO (Northwestern University Translational Research in Hematology-Oncology) Training Program

项目摘要 这项修订后的提案寻求为西北大学-血液学转化研究-提供资金。 肿瘤学(NU-TRIHO)培训计划，由血液学临床医生和科学家的迫切需求推动- 具有很高的积极性和充分的准备，能够在结合临床的职业生涯中投身并取得成功 实践和翻译研究。该计划的目标是让学员为挑战做好准备 等待下一代学术肿瘤学家--研究人员。它将提供教育和研究 整合和连接基础科学和临床科学的经验，从而为 翻译研究。它将授予技能，以补充他们的教育和研究经验，并 为他们在学术界的职业生涯做好准备。它将实施一项密集的职业发展计划，将 提供信息、咨询和帮助，帮助每位学员应对 建立成功的翻译研究事业。学员完成培训后，聘期为两年 一年西北大学内科或儿科血液肿瘤学临床培训 奖学金计划。17名实验室教师被选为项目教员，根据他们的 研究重点、资金和指导专业知识和能力。17名临床导师，他们有 在临床研究和与许多实验室主任合作方面取得了成功的记录 被选中促进翻译工作，提供职业建议，并参与指导研究 委员会。课程将为每个学员量身定做，由指导性实验室组成 和临床研究，完善沟通和授予写作技能的练习，指导阅读和 讨论，临床设计和指导方面的正式培训，负责任的研究指导方面的培训 作为对受训人员实验室和职业发展活动的补充的严谨和可重复性 临床调查。职业发展部分将提供信息、咨询和援助。 帮助每个实习生应对在建立成功的独立翻译系统时出现的挑战 研究生涯。建立了多种机制来评估NU-TRIHO的表现和成功 培训计划。该计划得到了卢里癌症中心和范伯格的大力机构支持 医学院的内科和儿科。拟议的NU-TRIHO培训计划 应对下一代学术血液学家和医学肿瘤学家面临的挑战 并解决了对更多精通临床相关基础科学的此类个人的迫切需求 研究、转化性研究和临床试验设计。

Project Summary This revised proposal seeks funding for the Northwestern University-Translational Research in Hematology- Oncology (NU-TRIHO) Training Program, prompted by the urgent need for clinician-scientists in Hematology- Oncology who are highly motivated and well-prepared to launch and succeed in careers that combine clinical practice and translational research. The objective of this program is to prepare trainees for the challenges awaiting the next generation of academic oncologist-researchers. It will provide educational and research experiences that integrate and bridge basic and clinical sciences, thereby establishing a solid foundation for translational research. It will confer skills that will complement their educational and research experiences and prepare them for careers in academia. It will implement an intensive career development program that will provide information, counseling, and assistance to help each trainee navigate the challenges faced in establishing a successful translational research career. Trainees will be appointed for two years after completing one year of clinical training in the Northwestern University Medicine or Pediatric Hematology-Oncology Fellowship programs. Seventeen laboratory preceptors have been selected as program faculty based on their research focus, funding, and mentoring expertise and capabilities. Seventeen clinical preceptors, who have successful track records in clinical research and collaborate with many of the laboratory preceptors, have been selected to facilitate translational efforts, provide career advice, and participate in mentoring research committees. The curriculum, which will be individually tailored to each trainee, consists of mentored laboratory and clinical research, exercises to refine communication and grant writing skills, guided readings and discussions, formal training in clinical design and conduct, training in the responsible conduct of research as well as rigor and reproducibility, and career development activities that complement the trainees’ laboratory and clinical investigations. The career development component will provide information, counseling, and assistance to help each trainee navigate the challenges that arise while establishing a successful independent translational research career. Multiple mechanisms are in place to evaluate the performance and success of the NU-TRIHO Training Program. The Program has strong institutional support from the Lurie Cancer Center and the Feinberg School of Medicine’s Departments of Medicine and Pediatrics. The proposed NU-TRIHO Training Program responds to the challenges faced by the next generation of academic hematologists and medical oncologists and addresses the critical need for more such individuals who are well-versed in clinically relevant basic science research, translational research, and clinical trial design.