Chemistry of Life Processes Predoctoral Training Program

项目摘要/摘要 在治疗疾病中遇到的跨越时间和长度的复杂问题需要广泛的技巧 技能，以及利用拥有各种不同专业知识的团队的能力来推动 新疗法和诊断学的发现。为了满足21世纪紧迫的公共卫生需求， 下一代研究人员必须能够用一种跨语言的共同语言思考和交流 化学和生物。拟议的生命过程化学(CLP)博士前培训的使命 西北大学的一项计划是招募、培训和提升一批不同的学生，这些学生 准备引领化学和生物学领域的下一波创新和发现。 CLP培训计划将针对培训生态系统的多个维度，并与NIGMS保持一致 博士前培训目标：以学生为中心的技能获取、学员的健康和保持、导师 发展、多样性、公平和包容性，以及评估和改进。中电计划将 为学生提供将化学和生命科学的研究生研究结合到一个学位的机会 超过了西北大学的任何培训项目。该计划建立在高度协作的基础上 52名导师的研究计划，这些导师在药物开发、诊断、 仿生分子，以及治疗干预的潜在分子靶点。它的深度和广度 课程要求、新颖的身临其境的跨学科实验室体验和独特的指导结构， 再加上强大的共享培训环境，使该项目有别于其他西北生物医学 培训计划。中电培训计划还通过以下方式提供对职业发展的高度关注 活动和计划，让学员接触到其他职业道路，促进与 潜在的导师，并培养沟通、简历开发和领导力方面的关键能力。这个 中电项目开发的循证培训方法和途径将与毕业生分享 西北大学和全国各地的计划，目标是最大限度地发挥计划创新的影响 为21世纪研究生教育的发展做出贡献。 此应用程序请求支持8个插槽/年(第1年；7个插槽)，在5年内总共支持39个插槽，以创建 有着共同身份的充满活力的同龄人。受训人员从毕业后的秋季开始获得助学金 在第二年和第三年的研究生教育中，他们都得到支持。另外十个 学生将得到为期一年的大学奖学金的支持，使合格和 不同的国际学生。该计划部署了基于团队的方法来进行计划领导， 利用其成员的独特专业知识和生命化学的管理能力 流程研究所，以加强项目开发、评估和评估，以及培训。

PROJECT SUMMARY/ABSTRACT The complex problems encountered across length and time scales in treating disease require a broad repertoire of skills along with the capacity to harness teams possessing a range of diverse expertise to advance the discovery of new therapeutics and diagnostics. To address the pressing public health needs of the 21st century, the next generation of researchers must be able to think and communicate in a common language that spans chemistry and biology. The mission of the proposed Chemistry of Life Processes (CLP) Predoctoral Training Program at Northwestern University is to recruit, train and advance a diverse cohort of students who are prepared to lead the next wave of innovation and discovery at the interface of chemistry and biology. The CLP Training Program will address multiple dimensions of the training ecosystem and is aligned with NIGMS goals for predoctoral training: student-centered skills acquisition, trainee wellness and retention, mentor development, diversity, equity and inclusion, and assessment and improvement. The CLP Program will provide students with the opportunity to integrate graduate studies in chemistry and the life sciences to a degree beyond that of any training program at Northwestern University. The program is built upon the highly collaborative research programs of 52 mentors with extensive expertise in the areas of drug development, diagnostics, biomimetic molecules, and potential molecular targets for therapeutic intervention. The depth and breadth of its coursework requirements, novel immersive cross-disciplinary lab experience, and unique mentoring structure, coupled with a strong shared training environment, set this program apart from other Northwestern biomedical training programs. The CLP Training Program also provides an intense focus on career development through activities and programs that will expose trainees to alternative career pathways, facilitate networking with potential mentors, and foster key competencies in communications, resume development, and leadership. The evidence-based training methods and approaches developed by the CLP Program will be shared with graduate programs at Northwestern and across the country with the goal of maximizing the impact of program innovations and contributing to the development of 21st century graduate STEM education. This application requests support for 8 slots/year (Year 1; 7 slots), for a total of 39 slots over 5 years to create a vibrant cohort of peers with a common identity. Trainees are appointed to the grant starting in the fall of their second year and are supported throughout their second and third years of graduate education. Ten additional students will be supported by one-year university fellowships, enabling the participation of well-qualified and diverse international students. The program deploys a team-based approach to program leadership that leverages the unique expertise of its members and the administrative capabilities of the Chemistry of Life Processes Institute to enhance program development, assessment and evaluation, and training.