Research and Capacity Building Core

尼日利亚是非洲人口最多的国家，癌症病例(11%)和死亡人数位居第二 (12%)在非洲。1现有以证据为基础的癌症控制干预措施，如癌症控制疫苗，但 在尼日利亚未得到充分利用。2，3为了缩小这一研究与实践的差距，我们提出了美国-尼日利亚癌症控制 实施科学与公平研究中心(C3-RISE)能力建设核心。整体而言 目标是增加尼日利亚早期职业调查人员和从业者的渠道，他们可以领导 正在对尼日利亚公平的癌症控制进行研究。我们将使用参与式实施科学 方法10(如众包11和学徒制)以发展可持续的执行能力 尼日利亚医学研究所的研究。众包要求一个团队来解决问题 (通过参与性活动，如公开募捐、12个指定马拉松、13个或其他活动)，然后分享 14学徒制度提供实践技能、直接指导和支持 增加实施IS干预措施的成功可能性的环境。在这个能力建设的核心中， 我们建议在IS方法中提供一系列面对面和在线培训机会，以激励创新、公平 癌症控制研究先导性研究。每年，公开招生将被用来确定八名优秀的受训人员 (作为两人团队的一部分)来自尼日利亚的参与机构(包括学术、临床和 基于社区的组织)。每个队列将参加为期两周的住院培训体验，重点是 是为了公平的癌症控制。学员还将成为为期一年的虚拟学习社区的一部分，并 旨在促进和维持IS和癌症工作人员职业生涯的指导计划。实习生团队 将竞争小型种子试点合作伙伴赠款，以在社区推出他们最终的IS癌症试点计划 网站。他们将接受资深教师导师的指导，以开展专注于增强 预防癌症的疫苗(即HPV和乙肝疫苗)。我们的具体目标是：识别和招募 尼日利亚受训人员为C3-Rise能力建设核心；2)发展为股权研究能力建设 在受训人员中开展癌症控制；以及3)发起、维持和评估虚拟参与式学习 社区促进了对经过管理的资源的访问以及分散在不同地理位置的 实习生。我们非常重视培养尼日利亚当地的导师和学员，这将对 使研究指导制度化，并加强组织一级的培训能力。我们的计划 与尼日利亚国家、国家卫生研究院和与癌症研究能力建设相关的战略优先事项保持一致。

Nigeria, Africa’s most populous country, bears the second highest burden of cancer cases (11%) and deaths (12%) in Africa.1 Evidence-based cancer control interventions such as vaccines for cancer control exist, but are underutilized in Nigeria.2,3 To close this research-to-practice gap, we propose a US-Nigerian Cancer Control Center for Research on Implementation Science and Equity (C3-RISE) capacity building core. The overall goals are to increase the pipeline of early-career Nigerian-based investigators and practitioners who can lead IS research for equitable cancer control in Nigeria. We will use participatory implementation science approaches10 (such as crowdsourcing11 and apprenticeships) to develop sustained capacity for implementation research at the Nigerian Institute of Medical Research. Crowdsourcing asks a group to solve a problem (through participatory activities such as open calls,12 designathons,13 or other activities) and then shares the solutions with the public.14 Apprenticeships provide the practical skills, direct mentorship, and supportive environment to increase the likelihood of launching successful IS interventions. In this capacity building core, we propose a series of in-person and online training opportunities in IS methods to spur innovative, equitable cancer control research pilot studies. Each year, open calls will be used to identify eight exceptional trainees (as part of two-person teams) from participating Nigerian-based institutions (including academic, clinical, and community-based organizations). Each cohort will join a two-week residential training experience focused on IS for equitable cancer control. Trainees will also become part of a year-long virtual learning community and mentoring program designed to facilitate and sustain careers in the IS and cancer workforces. Trainee teams will compete for small seed Pilot Partner grants to launch pilot plans of their final IS cancer pilots at community sites. They will receive mentorship from established faculty mentors to carry out pilots focused on enhancing vaccines to prevent cancer (i.e., HPV and HBV vaccines). Our specific aims are: To identify and recruit Nigerian trainees for the C3-RISE capacity building core ; 2) To develop IS research capacity building for equity in cancer control among trainees; and 3) To initiate, sustain, and evaluate a virtual participatory learning community to facilitate access to curated resources and collaboration between geographically dispersed trainees. Our strong focus on cultivating local Nigerian mentors and trainees will have an enduring impact on institutionalizing research mentorship and enhancing capacity for training at the organizational level. Our plan aligns with Nigerian national, NIH, and strategic priorities related to building capacity for cancer research.