Fellowship in Biological Psychiatry and Neuroscience

项目摘要 神经科学是发展最快的科学领域之一，并取得了令人瞩目的发展， 将对精神障碍的理解和治疗产生深远的影响。创新和 分子遗传学、脑成像方法、分子生物学和 史无前例的进步将理解和治疗精神障碍的视野扩展到 希望能预防甚至治愈它们。然而，在将知识和工具应用于 精神障碍，部分原因是缺乏临床和翻译科学研究人员。 因此，必须培养研究人员将重要的基础科学发现转化为临床。 相关治疗。 此竞争性续订申请要求为长期成功的NIMH继续提供资金 加州大学圣地亚哥分校(UCSD)生物精神病学和神经科学研究员。这个 奖学金旨在为7名博士后提供教育、研究培训和职业机会。 特别重视那些专注于使用生物工具理解 精神疾病的病理生理学和脑过程，并开发潜在的治疗方法 精神错乱。总体目标是培训来自不同背景的研究员，以获得必要的技能 生物精神病学和神经科学研究的概念化、规划、开展和出版 最终目标是成为独立的和有资金支持的研究人员。 该奖学金的具体目标是： (1)招募一批高水平的研究员进行高级研究培训 (2)提供成功过渡至独立研究所需的高水平培训 职业生涯，重点是：a)研究的道德行为和研究道德；b)一般方法 适用于生物精神病学和神经科学的研究；c)在研究中使用数据科学；d) 改进结果重现性的方法；e)与研究员个人有关的具体方法 研究项目；f)针对科学论文和补助金的科学写作培训 申请；；g)授予写作技能和有关NIH程序的教育 (3)使院士能够进行和完成可被视为 独立研究职业轨迹的种子，包括：a)基于 关于国立卫生研究院的表格和准则；b)在加州大学圣迭戈分校附属导师的指导下实施这一项目，以及c)定期 监测和评估研究进展情况。 (4)为职业发展提供切合实际的意见和支援，包括： 研究员介绍他们的项目和同行审查赠款申请，并模拟实践赠款审查 通过强制参加每周的教学会议进行评审；b)详细说明里程碑和职业生涯 编写在T32个人发展计划(IDP)中的指导方针；c)与高级研究人员建立网络 在加州大学可持续发展分校和其他组织内，并通过在线资源；d)研究员定期举行一对一会议 与董事进行科学和职业发展相关的指导和支持。

Project Summary Neuroscience is among the fastest growing area of science and has produced remarkable developments that will have profound implications for the understanding and treatment of mental disorders. Innovations and advancements in molecular genetics, brain imaging methods, molecular biology and have resulted in unprecedented advances that have extended visions of understanding and treating psychiatric disorders to the hope of preventing and even curing them. However, there is still a gap in applying knowledge and tools to psychiatric disorders that is due, in part, to a shortage of clinical and translational-science researchers. Consequently, it is imperative train researchers to translate important basic science findings into clinically relevant treatments. This competitive renewal application requests continued NIMH funding for the long-standing, successful University of California, San Diego (UCSD) Fellowship in Biological Psychiatry and Neuroscience. The Fellowship is designed for provide education, research training, and career opportunities for 7 post-doctoral fellows with a particular emphasis on candidates that are focused on using biological tools to understand pathophysiology and brain processes of psychiatric illness and develop potential treatments for these disorders. The overall goal is to train fellows from diverse backgrounds to acquire the skills necessary for the conceptualization, planning, conduct and publication of research in biological psychiatry and neuroscience with the ultimate goal to become independent and funded researchers. Specific goals of the Fellowship are: (1) To recruit a diverse group of highly accomplished fellows for advanced research training (2) To provide a high level of training necessary for successful transition into an independent research career, which is focused on: a) Ethical conduct of research and research ethics; b) General methodologies applicable to research in biological psychiatry and neuroscience; c) Use of data science in research; d) Methods to improve reproducibility of results; e) Specific approaches relevant for the fellow's individual research project; f) Training in scientific writing directed at production of scientific papers and grant applications.; g) Grant writing skills and education regarding NIH procedures (3) To enable the fellow to conduct and complete a specific research project that can be viewed as a seed for an independent research career trajectory and includes: a) Proposal of a research project based on NIH forms and guidelines; b) Implementation of this project with a UCSD-affiliated mentor, and c) Regular monitoring and evaluation of research progress. (4) To provide practical advice and support for career development, which includes: a) Opportunities for fellows to present their projects and peer-review grant applications, and practice grant review as a mock reviewer through mandatory attendance of the weekly didactic session; b) Explicate milestones and career guidelines that are written in the T32 Individual Development Plan (IDP); c) Network with senior researchers within UCSD and other organizations, and via online resources; d) Fellows have regular one-on-one meetings with directors for scientific and career development related mentoring and support.