Age related macular degeneration: novel ways to reduce vision loss through understanding a high-risk phenotype and validating a new early intervention.

老年性黄斑变性(AMD)是老年人视力丧失的主要原因。有网状假性玻璃体变性(RPD)的AMD眼现在被认为是进展更快的视力丧失的高危患者。确定驱动RPD的潜在机制对于确定特定靶向治疗方案至关重要。我们正在验证我们的阈值下激光试验，我们的早期终点将提供第一个经过验证的干预措施，以减缓AMD进展到视力丧失的速度。

Age-related macular degeneration (AMD) is the leading cause of vision loss in older individuals. AMD eyes with reticular pseudo drusen (RPD) are now recognised as at high-risk of faster progression to vision loss. Identifying the underlying mechanisms driving RPD is crucial for to identify specifically targeted therapeutic options. Validating our subthreshold laser trial, and our early endpoint will offer the first proven intervention to slow AMD progression to vision loss.