Washington University Paul Calabresi K12 Career Development Award for Clinical Oncology

华盛顿大学Paul Calabresi K12临床肿瘤学职业发展奖 项目总结/摘要 华盛顿大学（WU）Paul Calabresi K12职业发展奖（K12计划）的目标 临床肿瘤学是提供教学课程，指导研究实习和专业的职业生涯 为拥有医学博士、DO、药学博士学位的临床科学家、拥有博士学位的护士或同等学历的人提供的发展计划 ℃下我们建议更新K12，以继续培训来自不同学科的临床医生，包括 内科肿瘤学、外科肿瘤学、妇科肿瘤学、放射肿瘤学和儿科肿瘤学， 促进他们作为癌症研究人员的职业发展，并设计和管理假设驱动的 初步/I期、II期和III期癌症治疗临床试验。我们每年申请五个名额， 支持符合条件的学者获得两到三年的任用。为了加强我们非常成功的K12计划， 我们建议如下： 目标1：扩大训练有素的设计和执行严格的肿瘤临床研究的劳动力。我们 我建议在未来五年内每年在WU资助五个K12学者职位，以培训合格的申请人 来自不同的学科，专注于以患者为导向的癌症研究。 目标2：优化现有课程、职业发展、短期培训和指导性实践 与临床试验和以患者为导向的研究相关的研究经验。我们扩大了我们的 提供四个方面的培训机会：癌症基因组学，转化医学，以患者为中心 结果研究，癌症免疫学和细胞治疗。 目标3：继续发展和加强对K12学者，教师， 导师、课程和培训机会。我们将监测进展，展示成果，并使用 短期和长期结果，以改善临床肿瘤学研究培训。 成功地完成这些目标将导致更多的多样化，训练有素的调查人员， 领导假设驱动的癌症临床试验。通过在早期和整个过程中与利益攸关方合作， 翻译企业，他们将传播和实施他们的研究成果在真实的世界实践， 促进人类健康和医疗保健的迅速改善。

Washington University Paul Calabresi K12 Career Development Award for Clinical Oncology Project Summary / Abstract The goal of the Washington University (WU) Paul Calabresi K12 Career Development Award (K12 program) for Clinical Oncology is to provide didactic coursework, mentored research practicums and specialized career development programs for clinician scientists possessing an MD, DO, PharmD, nurses with PhDs, or equivalent degree. We propose the renewal of this K12 to continue training clinicians from diverse disciplines, including medical oncology, surgical oncology, gynecological oncology, radiation oncology and pediatric oncology to promote their career development as cancer researchers and to design and administer hypothesis-driven pilot/Phase I, Phase II, and Phase III cancer therapeutic clinical trials. We are requesting five slots per year to support eligible scholars for two to three-year appointments. To enhance our highly successful K12 program, we propose the following: Aim 1: Expand the workforce trained to design and execute rigorous oncologic clinical research. We propose to fund five K12 scholar positions per year at WU over the next five years to train eligible applicants from diverse disciplines focused on patient-oriented cancer research. Aim 2: Optimize existing curricula, career development, short-term training, and mentored, hands-on research experiences pertinent to clinical trials and patient oriented research. We expanded upon our opportunities to offer training in four tracks: Cancer Genomics, Translational Medicine, Patient Centered Outcomes Research, and Cancer Immunology and Cellular Therapy. Aim 3: Continue to develop and enhance robust evaluation and tracking of K12 scholars, faculty, mentors, curriculum, and training opportunities. We will monitor progress, demonstrate outcomes, and use short- and long-term results to improve clinical oncology research training. Successful completion of these aims will result in increased numbers of diverse, well-trained investigators who lead hypothesis driven cancer clinical trials. By partnering with stakeholders early and throughout the translational enterprise, they will disseminate and implement their research findings in real world practice to advance rapid human health and health care improvements.