2009 Salivary Glands and Exocrine Secretion Gordon Research Conference

描述（由申请人提供）：本提案寻求对将于2009年2月8日至13日在德克萨斯州加尔维斯顿加尔维斯顿酒店举行的第七届戈登唾液腺和外分泌研究会议的部分支持。这次会议是非常重要的，因为它是外分泌生物学领域杰出的多学科会议，因此汇集了唾液和外分泌腺研究人员，包括基础和翻译，以及来自相关领域的有前途的年轻科学家和专家。本次会议的总体目标是提供一个论坛，介绍和讨论尖端研究，旨在了解唾液腺和相关外分泌腺的生理学和病理生理学。第二个目标是促进和加强调查人员在这些相关领域的合作。为此，会议将突出与唾液腺和其他外分泌腺，包括胰腺，泪腺，肺和乳腺的研究人员分享的热点问题。该计划将由九个全体会议组成，包括两个主题演讲，其中包括具有国际地位的知名研究人员和两个海报会议。内容包括外分泌腺发育和再生的分子机制、干细胞、信号转导和基因调控、蛋白质和液体分泌。这些过程的失调在组织损伤中起作用，并且“外分泌疾病”如舍格伦综合征、干眼和胰腺炎的起始和进展也将是一个特定的特征。已经确定了广泛的国家和国际演讲者，其中包括有前途的年轻调查人员以及更成熟的调查人员。组织团队认识到有必要鼓励唾液腺和外分泌腺生物学的发展和进步，为此，我们将奋进特别鼓励年轻研究人员和新研究人员的参与。 公共卫生相关性：这次会议是高度健康相关的，因为它将促进讨论和优先考虑有关了解外分泌腺及其分泌物的病理生理学的重要未来研究方向。这次会议的一个特点将是对人类疾病的启动和发展的重点，从外分泌腺功能障碍，如干燥综合征，干眼和胰腺炎。辐射对唾液腺造成的组织损伤，以及防止损伤和/或再生唾液腺的策略也将是科学报告的重点。

DESCRIPTION (provided by applicant): This proposal seeks partial support for the seventh Gordon Research Conference on Salivary Glands and Exocrine Secretion to be held February 8-13th, 2009 at the Hotel Galvez, Galveston, Texas. This meeting is highly significant as it is the preeminent multi-disciplinary conference in the exocrine biology field, and as such brings together established salivary and exocrine gland investigators, both basic and translational with promising more junior scientists and experts from associated fields. The overall goal of this conference is to provide a forum for presentation and discussion of cutting edge research directed toward understanding the physiology and pathophysiology of the salivary gland and related exocrine glands. A secondary goal is to facilitate and strengthen collaborations between investigators in these related fields. To this end the conference will highlight the topical issues shared with researchers working in salivary and other exocrine glands including pancreas, lacrimal, lung and mammary gland. The program will be comprised of nine plenary sessions, and include two keynote addresses featuring established investigators of international stature, and two poster sessions. Topics to be covered include the molecular mechanisms involved in exocrine gland development and regeneration, stem cells, signal transduction and gene regulation, and protein and fluid secretion. The role dysregulation of these processes play in tissue damage, and the initiation and progression of "exocrineopathies" such as Sjogrens syndrome, dry eye and pancreatitis will also be a particular feature. A broad range of national and international speakers have been identified with the inclusion of promising young investigators as well as more established investigators. The organizing team recognizes the need to encourage the growth and advancement of salivary and exocrine gland biology and to this end we will endeavor to particularly encourage the participation of young investigators and investigators new to this field of research. PUBLIC HEALTH RELEVANCE: This conference is highly health related in that it will promote discussion and prioritization of the important future research directions pertinent to understanding the pathophysiology of exocrine glands and their secretions. A particular feature of this meeting will be a focus on the initiation and progression of human disease that arises from exocrine gland dysfunction, such as Sjogrens syndrome, dry eye and pancreatitis. Tissue damage to the salivary gland resulting from irradiation, and strategies to prevent damage and/or regenerate the gland will also be a focus of the scientific presentations.