Multiparameter Fiber Optic Breathing Sensor

描述(由申请人提供)：需要开发一种设备来检测周期性呼吸或短暂(20秒)中枢性或阻塞性呼吸暂停，与低氧血症有关，有婴儿猝死综合征(SID)的风险。一种非侵入性、经济高效、可靠和用户友好的呼吸监测仪可以提高安全性，并降低患有急性和病毒性呼吸道疾病的婴儿、儿童和成人的死亡风险。因此，研究和开发先进光学医疗诊断仪器的领先企业Redondo Optics，Inc.(ROI)建议开发一种新型、高精度和可靠、低成本、便携式和非侵入性的“ResHealth”设备，用于监测临床高危、危及生命、患有中枢性或阻塞性呼吸暂停、或有婴儿猝死综合征(SDS)风险的婴儿和儿童以及其他急性呼吸系统疾病患者的呼吸活动。在该计划的第一阶段，ROI将通过设计、组装和测试非侵入性多传感器阵列光学微芯片的概念原型，以及能够检测、分析和分离重要呼吸活动特征的光电传感器读出单元，最终展示ResHealth“监测设备的概念，并在发生潜在灾难性事件时生成警报，具有比传统监测系统更高的灵敏度、选择性和近乎错误的警报。在第二阶段，ROI将把ResHealth“监测设备集成到一个便携式、独立的单元中。这样的系统将立即在快速增长的呼吸监测和诊断市场中使用。目前市场上没有其他可用的商用设备以负担得起的价格提供这样的功能。与公众健康相关：在这一阶段，雷东多光学公司将设计和开发一种小型、高性价比、一次性的无线多传感器芯片，用于监测呼吸活动。拟议的传感器将允许评估患有中枢性或阻塞性呼吸暂停或小岛屿发展中国家的婴儿和儿童与低氧血症相关的重要呼吸功能，并可以通过减少对更昂贵的中央设施的需求来降低成本。

DESCRIPTION (provided by applicant): There is a need to develop devices for the detection of periodic breathing, or brief (<20- seconds) central or obstructive apnea, associated with hypoxemia for infants at risk of sudden infant death syndrome (SIDS). A non-intrusive, cost-effective, reliable, and user-friendly breathing monitor can improve the safety and reduce mortality risk to infants, children, and adults suffering from acute and viral respiratory disorders. For this reason, Redondo Optics, Inc., (ROI), a leader in the research and development of advanced optical medical diagnosis instrumentation, proposes to develop a new, highly accurate and reliable, low-cost, portable, and non-invasive, ResHealth" device for monitoring breathing activity in clinical high risk, life threatening, conditions associated with hypoxemia in infants and children suffering from central or obstructive apnea or at risk of sudden infant death syndrome (SIDS), and other acute respiratory breathing disorders. In Phase I of this program, ROI will conclusively demonstrate the concept of the ResHealth" monitoring device by designing, assembling, and testing a conceptual prototype of a non intrusive multi-sensor array optical microchip, and optoelectronic sensor readout unit capable of detecting, analyzing, and separating vital breathing activity signatures, and to generate an alarm in the case of a potential catastrophic event with higher sensitivity, selectivity, and with near false alarms, that conventional monitoring systems. In Phase II, ROI will integrate the ResHealth" monitoring device into a portable, stand-alone unit. Such a system will find an immediate use in the fast growing breathing monitors and diagnosis market. No other available commercial device in the market today offers such capabilities at an affordable cost. PUBLIC HEALTH RELEVANCE: In this Phase I, Redondo Optics will design and develop a small, cost-effective, disposable, wireless multi-sensor chip for monitoring breathing activity. The proposed sensor will permit assessment of vital breathing function associated with hypoxemia in infant and children suffering from central or obstructive apnea or SIDS and could decrease costs by reducing the need for more costly central facility.