The Role of Ethnic Racial Discrimination on the Development of Anxious Hypervigilance in Latina Youth

项目摘要/摘要 威胁警戒有助于自适应防御响应，在真正威胁的情况下是有利的。 然而，当极端和持续时，它可能会导致过度恐惧和回避，这是焦虑的核心特征。 焦虑的理论模型假设，对威胁的过度警惕可能会引发、维持或甚至加剧 焦虑症状。事实上，与健康参与者相比，焦虑症患者表现出更强的心理生理 在许多威胁预期状态下的反应和失调的神经回路功能。是否以及如何这样做 干扰受到与威胁相关的心理社会因素的影响，例如种族歧视 以及ER社会化，人们对此了解较少，特别是在焦虑风险上升的青春期。至 为了解决这一知识差距，目前的提议建立在现有的纵向研究的基础上，以检查 8-13岁拉丁裔青春期前女孩焦虑过度警惕的社会经历 表现出高度未经治疗的焦虑的群体，也有差异和过度暴露在ER中 歧视。这项建议的具体目的是(1)了解ER歧视对 拉丁裔女孩焦虑过度警觉的行为和神经生理指标，以及(2)探索主要和 父母内质网社会化对焦虑多警觉的调节作用及其与内质网的关系 分别是歧视和焦虑的高度警惕。焦虑的高度警戒性将在两个月内进行评估 基于任务的测量，通过对情绪模糊的面部刺激的社会判断，同情和 副交感神经反应和神经活动。儿童焦虑症状、ER歧视与父母ER 社会化将通过基于调查的措施进行评估。总而言之，通过这个项目，我将探索 ER歧视和ER社会化的纵向、生物学和社会后遗症，表征了父母 急诊室社会化实践作为潜在的保护因素，增强了我对神经生理学和 纵向数据分析，并有助于文化知情的干预和预防工作，旨在 减少小规模青年的焦虑。

Project Summary/Abstract Threat vigilance facilitates adaptive defensive responses and is advantageous in the case of real threats. However, when extreme and persistent, it can result in excessive fear and avoidance, core features of anxiety. Theoretical models of anxiety posit that hypervigilance towards threat may elicit, maintain, or even exacerbate anxiety symptoms. Indeed, relative to healthy participants, anxiety patients show greater psychophysiological responding and dysregulated neurocircuit function in many threat-anticipatory states. Whether and how such perturbations are impacted by threat-relevant psychosocial factors, such as ethnic-racial (ER) discrimination and ER socialization, is less well understood, particularly in adolescence when anxiety risk is elevated. To address this gap in knowledge, the current proposal builds on an existing longitudinal study to examine the social experiences that exacerbate anxious hypervigilance in preadolescent Latina girls aged 8-13 years, a group exhibiting high levels of untreated anxiety that is also differentially and excessively exposed to ER discrimination. The specific aims of this proposal are (1) to understand the effect of ER discrimination on behavioral and neurophysiological indices of anxious hypervigilance in Latina girls, and (2) to explore main and moderating effects of parental ER socialization on anxious hypervigilance and the association between ER discrimination and anxious hypervigilance, respectively. Anxious hypervigilance will be assessed during two task-based measures via social judgements of emotionally ambiguous face stimuli, sympathetic and parasympathetic responses, and neural activity. Child anxiety symptoms, ER discrimination, and parental ER socialization will be assessed via survey-based measures. In sum, through this project, I will explore possible longitudinal, biological, and social sequelae of ER discrimination and ER socialization, characterize parental ER socialization practices as potential protective factors, enhance my knowledge of neurophysiological and longitudinal data analysis, and contribute to culturally-informed intervention and prevention efforts aimed at reducing anxiety in minoritized youth.