Advancing the Study of Stroke in Women Through the Integration of Basic, Clinical, and Socioeconomic Perspectives

项目总结/摘要 尽管与男性相比，女性的特定年龄中风率较低，但中风对女性的生活影响不成比例。本次会议的目的是汇集多学科专家，早期职业和代表性不足的研究人员，详细介绍与女性中风相关的科学现状，讨论该领域的知识差距，并提出未来的研究计划，这些计划可以得到该小组和其他人的支持。会议将重点关注与女性卒中相关的三个相互关联的主题：1）女性和男性的社会和经济状况及其对卒中的影响，2）临床前研究确定的卒中性别差异机制，以及3）增加女性参与卒中相关随机临床试验。会议将扩大以前的合作和网络发起的多学科，特设工作组对中风的妇女-预防和结果，妇女加强中风的支持（PROWESS）。该会议旨在支持来自中风，性别差异和女性领域代表性不足的群体的初级教师和个人，目的是帮助他们开发与女性中风相关的重点假设驱动研究。这次会议将导致一个简要说明的传播和合作的发展，以推进未来的研究。

Project Summary/Abstract Despite lower age-specific rates of stroke in women compared to men, stroke has a disproportionate impact on the lives of women. The objective of this conference is to bring together multidisciplinary experts, and early career and underrepresented investigators to detail the current state of the science related to stroke in women, discuss knowledge gaps in the field, and propose future research initiatives that can be supported by this group and others moving forward. The conference will focus on three inter-related themes relevant to stroke in women: 1) social and economic circumstances of women and men and the impact on stroke, 2) mechanisms of sex differences in stroke as determined by pre-clinical research studies, and 3) increasing enrollment of women in stroke-related randomized clinical trials. The conference will expand on previous collaborations and networking initiated by the multidisciplinary, ad hoc working group on stroke in women -- Prevention and Outcomes in Women Enhancing Stroke Support (PROWESS). The conference has been designed to support junior faculty and individuals from underrepresented groups working in the area of stroke, sex differences, and women, with the goal of assisting them to develop focused hypothesis-driven research relevant to stroke in women. The conference will result in the dissemination of a summary statement and the development of collaborations to advance future research.