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中文摘要
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总结/摘要 此R13应用程序的目标是为2023年科学研究会议提供部分支持, 美国实验生物学学会联合会管理的血液肿瘤 (FASEB)。这个一年两次的会议是该领域的首要会议,为以下方面提供了宝贵的机会: 早期职业科学家与同行互动,并在该领域的领导建立调查人员在一个高度合议 和亲密的环境许多在该领域建立的调查人员看到他们出席这次会议 当他们还是实习生时,他们的职业发展以及帮助促进职业发展的能力至关重要 培养年轻的研究人员是这次会议吸引知名科学家的主要原因。临时 科学计划突出了血液学不同子领域最令人兴奋的科学 科学界非常感兴趣的恶性肿瘤主要课题包括:1)恶性造血干细胞 细胞生物学,2)正常造血发育,3)克隆造血和衰老,4)炎症和 造血,5)造血生态位,6)白血病基因表达程序的调节,6) 代谢和表观遗传学,和7)新的治疗策略。来自国际的两个主题演讲 该领域公认的领导人出席了会议。一些演讲时段是专门为 由初级研究者从摘要中选出口头报告。海报照明圆提供了一个 学员有机会在口头会议期间向听众介绍他们的工作,并确保海报 会议是会议最具互动性的部分之一。此R13中唯一的预算要求 申请是为50%的支持注册和住房费用的所有学员(研究生和 博士后研究员)谁将在本次会议上提出口头或海报报告。
英文摘要
SUMMARY/ABSTRACT The goal of this R13 application is to provide partial support to the 2023 Scientific Research Conference on Hematologic Malignancies administered by the Federation of American Societies for Experimental Biology (FASEB). This biannual conference is the premier meeting in the field, and provides invaluable opportunities for early-career scientists to interact with peers and leading established investigators in the field in a highly collegial and intimate setting. Numerous established investigators in the field see their attendance at this conference when they were trainees as pivotal to their career development, and the ability to help catalyze the career development of young investigators is a major draw for established scientists to this conference. The provisional scientific program highlights the most exciting science at the cutting edge of diverse sub-fields of hematologic malignancies of deep interest to the scientific community. Major topics include 1) malignant hematopoietic stem cell biology, 2) normal hematopoietic development, 3) clonal hematopoiesis and aging, 4) inflammation and hematopoiesis, 5) the hematopoietic niche, 6) regulation of leukemogenic gene expression programs, 6) metabolism and epigenetics, and 7) novel therapeutic strategies. Two keynote lectures from internationally recognized leaders in the field bookend the conference. A number of presentation slots are specifically dedicated to oral presentations by to junior investigators to be selected from abstracts. Poster Lighting Rounds provide an opportunity for trainees to introduce the audience to their work during oral sessions, and ensure that the poster sessions are one of the most interactive parts of the conference. The sole budgetary request in this R13 application is for 50% support of the registration and housing costs for all trainees (graduate students and postdoctoral fellows) who will present oral or poster presentations at this conference.
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Defining and targeting asparaginase resistance mechanisms in high-risk acute leukemias
  • 批准号:
    10415133
  • 项目类别:
  • 资助金额:
    $43.37万
  • 财政年份:
    2015
  • 负责人:
    Alejandro Gutierrez
  • 依托单位:
Defining and targeting asparaginase resistance mechanisms in high-risk acute leukemias
  • 批准号:
    9981054
  • 项目类别:
  • 资助金额:
    $45.39万
  • 财政年份:
    2015
  • 负责人:
    Alejandro Gutierrez
  • 依托单位:
Discovery and targeting of apoptosis resistance mechanisms in high-risk T-ALL
  • 批准号:
    9116144
  • 项目类别:
  • 资助金额:
    $45.11万
  • 财政年份:
    2015
  • 负责人:
    Alejandro Gutierrez
  • 依托单位:
Defining and targeting asparaginase resistance mechanisms in high-risk acute leukemias
  • 批准号:
    10172856
  • 项目类别:
  • 资助金额:
    $45.05万
  • 财政年份:
    2015
  • 负责人:
    Alejandro Gutierrez
  • 依托单位:
海外基金