Integrated and Translational Training in Anesthesiology Research

描述（由申请人提供）：在过去的40年里，麻醉师已经成为基础科学和临床研究的重要贡献者。为了有效，这项研究需要增加对基础生理学，药理学，遗传学，分子生物学，生物工程，流行病学和生物统计学的理解。如果麻醉学要继续提高为年龄不断增长的日益复杂的患者群体提供护理的安全性，并继续吸引最有能力的护理提供者进入该专业，我们必须在临床护理和研究方面提供最好的培训。我们认为，为了保持研究工作的临床相关性，保持麻醉师作为科学家的培训至关重要。近年来，科学发现的快速发展为将基础科学发现直接应用于疾病患者提供了巨大的机会。在基础科学和临床研究方面的严格培训是优化这种类型的转化研究的关键。该计划的目标是提供基础和临床科学培训学术麻醉师作为其研究生临床培训计划的一个组成部分。该培训将允许麻醉师建立独立的调查职业，致力于通过推进该领域的知识来改善麻醉/危重患者的护理。该提案概述了一个多元化但有凝聚力的教师谁愿意并准备满足这一目标的凭据。该培训计划涉及为期两年的连续性，学员在神经科学，性别生物学，肺生物学，心血管，肾脏，代谢和疼痛研究领域的教员的密切监督下工作。最初，学员将学习研究技能，后来的重点将转向独立的假设生成，实验设计，数据分析，研究结果的展示以及外部资金的竞争。研究机会由具有博士后研究员培训成功记录的教师提供，无论是来自麻醉学内部还是来自其他合作基础科学和临床部门：神经病学，医学，神经科学，儿科，神经外科，病理学，生理学和药理学。该计划的目的是产生学术麻醉师谁将提供整个世纪的学术领导。

DESCRIPTION (provided by applicant): Over the past 40 years, anesthesiologists have become increasingly important contributors to both basic science and clinical research. To be effective, this research has required an increased understanding of basic physiology, pharmacology, genetics, molecular biology, bioengineering, epidemiology, and biostatistics. If anesthesiology is to continue to improve the safety of care provided to an increasingly complicated group of patients of increasing age and to continue to attract the most competent care providers into the specialty, we must provide the best training possible, both in clinical care and research. We believe it is crucial to maintain training of anesthesiologists as scientists in order to maintain the clinical relevance of research endeavors. The rapid progression of scientific discovery in recent years, offers remarkable opportunities for direct application of basic scientific findings to patients with disease. Rigorous training in both basic science and clinical research is the key to optimize this type of translational research. The goal of this program is to provide basic and clinical scientific training to academic anesthesiologists as an integral component of their postgraduate clinical training program. This training will allow anesthesiologists to establish independent investigative careers devoted to improving care of the anesthetized/critically ill patient by advancing knowledge in the field. This proposal outlines the credentials of a diverse but cohesive faculty who are willing and prepared to meet this objective. The training program involves a two year continuum where trainees work under close supervision of a faculty member in research areas of neuroscience, gender biology, lung biology, cardiovascular, kidney, metabolism, and pain. Initially, the trainee will learn research skills, and later emphasis will be directed towards independent hypothesis generation, experimental design, data analysis, presentation of research findings, and competition for external funding. Research opportunities are offered by faculty members with proven records of success in the training of postdoctoral fellows, both from within Anesthesiology as well as from other collaborating basic science and clinical departments: neurology, medicine, neuroscience, pediatrics, neurosurgery, pathology, and physiology & pharmacology. This program is designed to produce academic anesthesiologists who will provide academic leadership throughout this century.