Administrative and Clinical Support

核心A将监督本项目中概述的各种临床和实验室研究的行政协调。它将整合项目内部和项目之间的科学和临床工作，并确保将实验室发现转化为临床；相反，从临床观察开始的实验室研究。在之前的资助期间，已经建立了基础设施，以便在项目之间进行顺畅的沟通和数据交换，促进临床前研究和临床试验的合作。多个联合出版物，已完成和正在进行的临床试验，以及几种新型靶向疗法从实验室到床边的转化，证实了我们努力的沟通和整合。该核心将继续促进项目成员之间以及内部和外部咨询委员会之间的信息交流。为拟进行的临床试验提供临床研究护理支持。此外，与前一个供资期间一样，临床研究协调员将确保适当的样本采集和贩运。拨款管理人会适时及统筹地分配资源，以协助成功完成拟议的研究。核心A将提供这些

Core A will oversee the administrative coordination of the various clinical and laboratory studies outlined in this Program Project. It will integrate scientific and clinical efforts within and between Projects, and assure the translation of laboratory findings to the bedside; and conversely, the initiation of laboratory studies stemming from clinical observations. During the prior funding period, the infrastructure has been created to have seemless communication and exchange of data between Projects, facilitating collaborative preclinical studies and clinical trials. Multiple joint publications, completed and ongoing clinical trials, and the translation of several novel targeted therapies from bench to bedside confirm the communication and integration of our efforts. This Core will continue to facilitate exchange of information among the Program members, as well as the internal and external advisory committees. It will provide clinical research nursing support for the proposed clinical trials. In addition, as in the previous funding period, a clinical study coordinator will assure appropriate sample acquisition and trafficking. The grants administrator will allocate resources in a timely and integrated fashion to facilitate successful completion of the proposed studies. Core A will provide these functions: 1. To integrate scientific and clinical efforts within and between Projects 2. To assure translation of laboratory findings to the bedside; and conversely, the initiation of laboratory studies stemming from clinical observations. 3. To provide administrative support for the Projects.