VISUALIZATION ENVIRONMENTS FOR MULTI-SCALE BIOMEDICAL MODELING

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本研究的目标是开发一个基于组件的可视化环境，这是有用的范围广泛的 生物科学家致力于研究各种尺度的分子结构功能关系， 数据类型环境支持从基因序列到原子结构的结构信息 细节，从电子显微镜和光学显微镜重建的数据。随着基因组计划扩展到 在功能基因组学领域，对可视化工具的需求越来越大，这些工具可以将数据和计算从 在生物物理范围内。从序列数据、单个分子和基因组数据开发复杂模型的可能性 生物样品的结构和成像将取决于支持以下的计算和可视化环境： 多模式和多规模的能力。通过利用基于组件的交互基础设施，我们将能够 有效地设计和构建可视化工具，以满足计算环境日益增长的需求。 生物学社区，并将融入基于网络的计算和协作环境。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goal of this research is to develop a component-based visualization environment that is useful to a broad range of biological scientists working on aspects of molecular structure function relationships at various scales and with a variety of data types. The environment supports structural information that ranges from gene sequence and structure at atomic detail, to data reconstructed from electron microscopy, and light microscopy. As the Genome Initiative expands into the area of functional genomics, there is an increasing need for visualization tools that integrate data and computation from across the biophysical range. The possibility of developing complex models from sequence data, individual molecular structures, and imaging of biological samples will depend upon computational and visualization environments that support multi-modal and multi-scale capabilities. By capitalizing on the component-based interaction infrastructure, we will be able to efficiently and effectively design and build visualization tools that are tailored to the growing needs of the computational biology community, and that will integrate into network based computational and collaborative environments.