DEVELOPMENTAL BIOLOGY PROGRAM

发育生物学(DB)计划的中心主题是癌症通常是腐败的结果 发展性监管网络。我们努力利用MODEL中强大的分子遗传学 了解支持正常发育的基本信号过程，以及 这些通路中的异常可能导致癌症。目标是为以下目标提供关键的新目标 化学预防和化学治疗干预。 计划成员：自上次更新以来，发育生物学计划经历了几次 领导层的更迭。布莱恩特博士辞去项目负责人一职，专注于振兴研究生 他被授予分子生物学、遗传学和生物化学专业学位，并由布隆伯格博士接替。在他的工作之后 随着研究生项目主任的任期结束，布莱恩特博士于2006年重新加入该项目，成为该项目的联合负责人，接替他的是布莱恩特博士。 马什在2007年。博德和法伦博士退休，布拉赫曼博士过渡到准会员。新的 成员包括从广州市搬来的Maike Sander博士和Peter Donovan博士，黄桃生，Tom 希林和加入该计划的拉胡尔勇士。 DB计划有16名成员，代表五个部门和两所学校，在#年有5019,083美元 与癌症相关的直接同行审查资助，其中1个项目由NCI资助，直接总额为 152,000美元。在2007年，会员共出版了28本刊物，其中18本与癌症有关。 其中22%是内部关系，6%是内部关系。

The central theme of the Developmental Biology (DB) Program is that cancer is often the result of corrupted developmental regulatory networks. We strive to use the powerful molecular genetics available in model organisms to understand fundamental signaling processes underlying normal development, and the abnormalities in these pathways that can lead to cancer. The goal is to provide key new targets for chemopreventive and chemotherapeutic interventions. Program Membership: Since the last renewal, the Developmental Biology Program has undergone several leadership changes. Dr. Bryant stepped down as the program leader to focus on rejuvenating the Graduate Program in Molecular Biology Genetics and Biochemistry and was replaced by Dr. Blumberg. After his stint as Graduate director ended, Dr. Bryant rejoined the program as Co-Leader in 2006 and was replaced by Dr. Marsh in 2007. Drs. Bode and Fallon retired and Dr. Brachmann transitioned to Associate Member. New Members include Dr. Maike Sander who moved from GF, and Drs. Peter Donovan, Taosheng Huang, Tom Schilling, and Rahul Warrior who joined the Program. The DB Program has 16 Members, representing five Departments and two Schools, and has $5,019,083 in direct cancer-related peer-reviewed funding, 1 project of which is funded by NCI for a direct total of $152,000. In 2007, Members published a total of 28 publications with 18 of those being cancer-related of which 22% were inter- and 6% were intra-related.