HIV/AIDS: Translational Approaches and Health Disparities

描述（由申请人提供）：最近，国家精神卫生研究所（NIMH）强调需要增加少数民族研究科学家的数量，因为美国缺乏联邦政府资助的少数民族研究人员。非裔美国人、西班牙裔美国人和美洲印第安人占美国人口的24%，他们只向NIMH提交了5.2%的申请，因此只有3.9%的申请人获得资助。在提交和资助的非裔美国人和拉丁美洲人，特别是这种差距也反映在美国国立卫生研究院和中心的资助模式。已经认识到需要为博士后研究员和早期职业教师制定研究指导计划，以提高在艾滋病毒/艾滋病、精神健康、药物滥用及其相关差异方面进行高质量文化一致性研究的能力。在美国，特别是在南加州，少数种族和少数民族（REM）感染艾滋病毒/艾滋病和患有精神疾病和药物滥用的人数过多，而REM研究人员在这些地区的人数不足，这一问题已得到明确记录，需要加以解决。这项拟议的R25培训补助金，加州大学洛杉矶分校REM艾滋病毒/艾滋病转化培训（HATT） 该计划将为对研究艾滋病毒/艾滋病、心理健康和药物滥用以及相关的共病差异感兴趣的REM调查人员制定一个研究指导计划。该方案还将建立一个暑期研究所，由艾滋病毒/艾滋病、精神健康和药物滥用行为、基础和临床研究领域的专家组成的高级导师网络。在加州大学洛杉矶分校文化，创伤和心理健康差异中心（CCTMHD），艾滋病毒识别，预防和治疗服务中心（CHIPTS）和加州大学洛杉矶分校艾滋病研究所等的大力支持下，8名博士后研究员和初级研究员将在两年内接受最先进的培训。这些REM研究人员还将促进跨学科研究，研究和阐明与艾滋病毒/艾滋病，心理健康，药物滥用及其相关的种族和少数民族之间的差异相关的行为，生物和心理因素。加州大学洛杉矶分校指导委员会，沿着与科学咨询委员会（SAC），将进行全国申请过程中选择博士后和早期职业研究候选人。研究指导将包括：（1）为期六周的暑期研究所，包括教学讲座和个性化的指导和咨询;（2）通过网络广播电信进行长期的现场研究指导和指导，以指导和监测实现研究目标的进展。指导委员会、SAC成员、导师、国家顾问和REM调查员将每年对培训方案进行两次评估。还将进行长期的研究职业跟踪，以确保REM研究人员指导其他人将培训扩展到第二代NIH研究人员。

DESCRIPTION (provided by applicant): Recently, the National Institute of Mental Health (NIMH) has highlighted the need to increase the number of minority research scientists, as there exists a dearth of federally funded minority investigators in the United States. African Americans, Hispanics and American Indians, who collectively comprise 24% of the U.S. population, submitted only 5.2% of all applications to NIMH, resulting in only 3.9% of funded applicants. This disparity in the submission and funding of grants by African Americans and Latinos in particular is also reflected in funding patterns by NIH Institutes and Centers. The need to develop research mentoring programs for postdoctoral fellows and early career faculty to improve the capacity for high quality culturally congruent research in HIV/AIDS, mental health, substance abuse, and their associated disparities has been recognized. The overrepresentation of racial and ethnic minority (REM) individuals living with HIV/AIDS and suffering from mental illness and substance abuse in the United States but especially in Southern California, and an under-representation of REM researchers in these areas has been clearly documented and needs to be addressed. This proposed R25 training grant, the UCLA REM HIV/AIDS Translational Training (HATT) Program, will develop a research mentorship program for REM investigators interested in studying HIV/AIDS, mental health and substance abuse and associated co-morbid disparities. This program will also establish a summer institute with a network of senior mentors who are experts in the field of behavioral, basic, and clinical research of HIV/AIDS, mental health and substance abuse. With significant support from the UCLA Center for Culture, Trauma and Mental Health Disparities (CCTMHD), The Center for HIV Identification, Prevention and Treatment Services (CHIPTS) and the UCLA AIDS Institute and others, 8 postdoctoral fellows and junior investigators will receive state-of-the-art training over two years. These REM investigators will also promote interdisciplinary research that examines and elucidates the behavioral, biological, and psychological factors associated with HIV/AIDS, mental health, substance abuse and their associated disparities among racial and ethnic minorities. The UCLA Steering Committee, along with the Scientific Advisory Committee (SAC), will conduct a national application process to select post-doctoral and early career research candidates. Research mentoring will include: (1) a six-week summer institute composed of didactic lectures and individualized mentoring and consultation and; (2) ongoing long-term onsite research mentoring and mentoring via webcast telecommunication to guide and monitor progress toward research goals. The Steering Committee, SAC members, mentors, national consultants and REM investigators will evaluate the training program twice each year. Long-term research career follow-up will also be conducted to ensure that REM Investigators mentor others to extend the training into a second generation of NIH researchers.